Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues.
W Croteau, JC Davey, VA Galton… - The Journal of clinical …, 1996 - Am Soc Clin Investig
The deiodination of thyroid hormones in extrathyroidal tissues plays an important role in
modulating thyroid hormone action. The type II deiodinase (DII) converts thyroxine to the …
modulating thyroid hormone action. The type II deiodinase (DII) converts thyroxine to the …
The deiodinase family: selenoenzymes regulating thyroid hormone availability and action
J Köhrle - Cellular and Molecular Life Sciences CMLS, 2000 - Springer
Thyroid hormones control growth, development, differentiation and metabolism in
vertebrates. Most of the actions of the active thyroid hormone T3 (3, 5, 3′-triiodo-l …
vertebrates. Most of the actions of the active thyroid hormone T3 (3, 5, 3′-triiodo-l …
Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone
HM Tu, SW Kim, D Salvatore, T Bartha… - …, 1997 - academic.oup.com
To identify the specific locations of type 2 deiodinase (D2) messenger RNA (mRNA) in the
hypothalamus and pituitary gland and determine its regulation by thyroid hormone, we …
hypothalamus and pituitary gland and determine its regulation by thyroid hormone, we …
Role of iodine, selenium and other micronutrients in thyroid function and disorders
V Triggiani, E Tafaro, VA Giagulli… - … Metabolic & Immune …, 2009 - ingentaconnect.com
Micronutrients, mostly iodine and selenium, are required for thyroid hormone synthesis and
function. Iodine is an essential component of thyroid hormones and its deficiency is …
function. Iodine is an essential component of thyroid hormones and its deficiency is …
The trace element selenium and the thyroid gland
J Köhrle - Biochimie, 1999 - Elsevier
Apart from the essential trace element iodine, which is the central constitutent of thyroid
hormones, a second essential trace element, selenium, is required for appropriate thyroid …
hormones, a second essential trace element, selenium, is required for appropriate thyroid …
Selenium as a pleiotropic agent for medical discovery and drug delivery
B Guan, R Yan, R Li, X Zhang - International journal of …, 2018 - Taylor & Francis
Selenium as a biologically active element lends much support to health maintenance and
disease prevention. It is now presenting pleiotropic effects on therapy and drug delivery. In …
disease prevention. It is now presenting pleiotropic effects on therapy and drug delivery. In …
An overview of the ongoing insights in selenium research and its role in fish nutrition and fish health
In the present review, the ongoing researches about selenium research in fish nutrition have
been comprehensively discussed. Selenium research is getting popularity in fish nutrition as …
been comprehensively discussed. Selenium research is getting popularity in fish nutrition as …
Regional expression of the type 3 iodothyronine deiodinase messenger ribonucleic acid in the rat central nervous system and its regulation by thyroid hormone
HM Tu, G Legradi, T Bartha, D Salvatore… - …, 1999 - academic.oup.com
Abstract Type 3 iodothyronine deiodinase (D3) is a selenoenzyme that inactivates thyroid
hormone. It is necessary for T3 homeostasis in the central nervous system. D3 activity has …
hormone. It is necessary for T3 homeostasis in the central nervous system. D3 activity has …
Selenium and the control of thyroid hormone metabolism
J Köhrle - Thyroid, 2005 - liebertpub.com
Thyroid hormone synthesis, metabolism and action require adequate availability of the
essential trace elements iodine and selenium, which affect homeostasis of thyroid hormone …
essential trace elements iodine and selenium, which affect homeostasis of thyroid hormone …
[HTML][HTML] Cloning and expression of a cDNA for a mammalian type III iodothyronine deiodinase
W Croteau, SL Whittemore, MJ Schneider… - Journal of Biological …, 1995 - ASBMB
The type III iodothyronine deiodinase metabolizes the active thyroid hormones thyroxine and
3, 5, 3'-triiodothyronine to inactive compounds. Recently, we have characterized a Xenopus …
3, 5, 3'-triiodothyronine to inactive compounds. Recently, we have characterized a Xenopus …