Synthesis and biological properties of 2 (5H)-furanones featuring bromine atoms on the heterocyclic ring and/or brominated substituents

R Rossi, M Lessi, C Manzini… - Current Organic …, 2017 - ingentaconnect.com
This review deals with the synthesis of unnatural and natural 2 (5H)-furanone derivatives
featuring bromine atoms on the heterocyclic ring and/or brominated substituents, which have …

3, 5-Disubstituted pyranone analogues of highly antifungally active furanones: conversion of biological effect from antifungal to cytostatic

R Schiller, L Tichotová, J Pavlík, V Buchta… - Bioorganic & medicinal …, 2010 - Elsevier
A series of 3-aryl-5-acyloxymethyl-5, 6-dihydro-2H-pyran-2-ones, related to highly
antifungally active butenolides, was synthesized via cyclization of substituted δ-hydroxy …

A facile synthesis of phenylacetic acids via Willgerodt-Kindler reaction under PTC condition

M Mujahid Alam, SR Adapa - Synthetic communications, 2003 - Taylor & Francis
Phenylacetic acids are efficiently synthesized from acetophenones via thiomorpholides
under Phase Transfer Catalytic (PTC) condition. The reaction proceeds efficiently by using …

In vitro antifungal activity of 3-phenyl-2H-benzoxazine-2,4(3H)-diones

K Waisser, L Kubicova, V Buchta, P Kubanova… - Folia microbiologica, 2002 - Springer
Abstract A series of 81 3-phenyl-2 H-benzoxazine-2, 4 (3 H)-diones with substitution at C (6)
on the benzoxazine ring and on the phenyl moiety was synthesized; the compounds were …

Cycloisomerization of olefinic carboxylic acids catalyzed by trifluoromethanesulfonic acid

L Coulombel, E Duñach - Synthetic communications, 2005 - Taylor & Francis
Full article: Cycloisomerization of Olefinic Carboxylic Acids Catalyzed by Trifluoromethanesulfonic
Acid Skip to Main Content Taylor and Francis Online homepage Taylor and Francis Online …

Antifungal 3, 5-disubstituted furanones: From 5-acyloxymethyl to 5-alkylidene derivatives

P Šenel, L Tichotová, I Votruba, V Buchta… - Bioorganic & Medicinal …, 2010 - Elsevier
5-Acetoxymethyl-3-(4-bromophenyl)-2, 5-dihydrofuran-2-one previously described as highly
antifungally active was found to provide the corresponding 5-methylene derivative via an …

Tellurium in organic synthesis: synthesis of bioactive butenolides

BK Bassora, CE Da Costa, RA Gariani, JV Comasseto… - Tetrahedron letters, 2007 - Elsevier
Reduction of (Z)-β-butyltelluro-enones gives the corresponding γ-hydroxy vinylic tellurides
with retention of the double bond configuration. Reaction of γ-hydroxy vinylic tellurides with …

Chiral δ-iodo-γ-lactones derived from cuminaldehyde, 2, 5-dimethylbenzaldehyde and piperonal: Chemoenzymatic synthesis and antiproliferative activity

W Gładkowski, A Skrobiszewski, M Mazur… - Tetrahedron …, 2016 - Elsevier
Six enantiomeric pairs of β-aryl-δ-iodo-γ-lactones 8a–c, 9a–c derived from cuminaldehyde,
2, 5-dimethylbenzaldehyde and piperonal were synthesized with high enantiomeric purities …

In vitro activities of 3-(halogenated phenyl)-5-acyloxymethyl-2, 5-dihydrofuran-2-ones against common and emerging yeasts and molds

V Buchta, M Pour, P Kubanová, L Silva… - Antimicrobial agents …, 2004 - Am Soc Microbiol
ABSTRACT Three 3-(halogenated phenyl)-5-acyloxymethyl-2, 5-dihydrofuran-2-ones were
evaluated for activity against 191 strains of common and emerging yeasts and Aspergillus …

Ring‐Closing Metathesis Enabled Efficient Synthesis of γ‐Butenolide Antifungal Agent (−)‐Incrustoporin and its Analogues

RA Fernandes, PH Patil… - Asian Journal of Organic …, 2014 - Wiley Online Library
An efficient synthesis of the antifungal agent (−)‐incrustoporin and analogues based on ring‐
closing metathesis (RCM) is described. The ready availability of various allyl alcohols …