Despite numerous studies on the neurobiology of depression, the etiological and
pathophysiological mechanisms of this disorder remain poorly understood. A large number …

Ethnopharmacological relevance Liquiritin is a flavonoid derived from Radix et Rhizoma
Glycyrrhizae, which is a widely used traditional Chinese medicine with the effects of …

Objective: Determine whether a novel psychosocial treatment for positive affect improves
clinical status and reward sensitivity more than a form of cognitive behavioral therapy that …

Background The immune system has major roles in the brain and related psychopathology.
Disrupted interleukin-6 secretion and aberrant amygdala emotional reactivity are well …

Speech carries essential information about the speaker's physiology and possible
pathophysiological conditions. Bio-acoustic voice qualities show promising value for …

We describe evidence for dissociable roles of the medial and lateral orbitofrontal cortex
(OFC) in major depressive disorder (MDD) from structure, functional activation, functional …

Abstract ARNSTEN, AFT, MKP Joyce and AC Roberts. The Aversive Lens: Stress effects on
the prefrontal-cingulate cortical pathways that regulate emotion. NEUROSCI BIOBEHAV …

Objective Anhedonia is a core feature of major depressive disorder (MDD), and as a subtype
of depression, MDD with anhedonia may have exceptional neurobiological mechanisms …

Conventional monoamine-based pharmacotherapy, considered the first-line treatment for
major depressive disorder (MDD), has several challenges, including high rates of non …

Dopamine (DA), the most abundant human brain catecholaminergic neurotransmitter,
modulates key behavioral and neurological processes in young and senescent brains …