Genetics of the polycystic ovary syndrome

G Kosova, M Urbanek - Molecular and cellular endocrinology, 2013 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly complex endocrine disorder, characterized by
hyperandrogenemia, menstrual irregularities and polycystic ovaries. A strong genetic …

Molecular & genetic factors contributing to insulin resistance in polycystic ovary syndrome

S Mukherjee, A Maitra - Indian Journal of Medical Research, 2010 - journals.lww.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of unknown
etiology. Insulin resistance is very common and plays a central pathogenic role in PCOS …

Genetic studies on polycystic ovary syndrome

H Zhao, Y Lv, L Li, ZJ Chen - Best practice & research Clinical obstetrics & …, 2016 - Elsevier
Highlights•This paper sorts out most of the polycystic ovary syndrome (PCOS)-related
candidate genes and highlights some of the key genes.•A review of the results of recent …

Роль антимюллерова гормона (АМГ) в норме и при различных гинекологических заболеваниях

КЮ Боярский, СН Гайдуков… - Журнал акушерства и …, 2009 - cyberleninka.ru
•· В представленном обзоре рассмотрены различные аспекты использования
измерения АМГ в гинекологической практике. АМГ является гормоном …

[HTML][HTML] The VNTR in complex disorders: the forgotten polymorphisms? A functional way forward?

KJ Brookes - Genomics, 2013 - Elsevier
In the last few years, research has focused on single nucleotide polymorphisms (SNPs) in
the search for underlying genetic aetiology of complex disorders. This has been afforded by …

Genetic markers of polycystic ovary syndrome: emphasis on insulin resistance

N Shaikh, R Dadachanji… - International Journal of …, 2014 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of
childbearing age causing not only reproductive but also metabolic anomalies. PCOS women …

Effect of hyperinsulinaemia and insulin resistance on endocrine, metabolic and fertility outcomes in women with polycystic ovary syndrome undergoing ovulation …

D Zhang, X Yang, J Li, J Yu, X Wu - Clinical Endocrinology, 2019 - Wiley Online Library
Objective The aim of this study was to evaluate the effects of hyperinsulinaemia and insulin
resistance (IR) on reproductive and metabolic disorders and fertility in women with polycystic …

Pathway analysis based on a genome-wide association study of polycystic ovary syndrome

U Shim, HN Kim, H Lee, JY Oh, YA Sung, HL Kim - PloS one, 2015 - journals.plos.org
Background Polycystic ovary syndrome (PCOS) is one of the most common endocrine
disorders in women of reproductive age, and it is affected by both environmental and genetic …

[PDF][PDF] 胰岛素, 瘦素, 雄激素与多囊卵巢综合征发病机制研究进展

金华良, 王兴娟 - 复旦学报: 医学版, 2010 - jms.fudan.edu.cn
摘要! 多囊卵巢综合征! 53< R-R47'-3 ($. R4R%#. 3;+# A2F," 是一种发病呈多因性'临床表现呈
多态性的内分泌紊乱综合征& 其发病机制至今尚未阐明# 既往研究认为高胰岛素血症与高雄 …

SNP rs2470152 in CYP19 is correlated to aromatase activity in Chinese polycystic ovary syndrome patients

XL Zhang, CW Zhang, P Xu… - Molecular …, 2012 - spandidos-publications.com
CYP19 encodes aromatase, a key enzyme essential for estrogen biosynthesis. Single
nucleotide polymorphism (SNP) rs2470152 in CYP19 is associated with serum estradiol …