Lumbar disc degeneration is one of the leading causes of chronic low back pain. The
degenerative cascade is often initiated by an imbalance between catabolic and anabolic …

Intervertebral disc (IVD) degeneration (IDD) is a multifactorial pathological process
associated with low back pain (LBP). The pathogenesis is complicated, and the main …

Intervertebral disc (IVD) degeneration (IVDD) is a leading cause of chronic low back pain.
There is a strong clinical demand for more effective treatments for IVDD as conventional …

Intervertebral disk degeneration (IVDD) is a leading cause of disability. The degeneration is
inevitable, and the mechanisms are complex. Current therapeutic strategies mainly focus on …

Intervertebral disc degeneration (IDD) is a major contributor to back, neck, and radicular
pain. It is related to changes in tissue structure and function, including the breakdown of the …

Intervertebral disc degeneration (IDD), a progressive and multifactorial pathological process,
is predominantly associated with low back pain and permanent disability. Pyroptosis is a …

The human intervertebral disc (IVD) is a complex organ composed of fibrous and
cartilaginous connective tissues, and it serves as a boundary between 2 adjacent vertebrae …

Recently published clinical trials involving the use of adipose-derived stem cells (ADSCs)
indicated that approximately one-third of the studies were conducted on musculoskeletal …

Background Low back pain is a common symptom of intervertebral disc degeneration (IDD),
which seriously affects the quality of life of patients. The abnormal apoptosis and …

Low back pain (LBP) is one of the leading causes of disability worldwide, with a significant
socioeconomic burden on healthcare systems. It is mainly caused by degenerative disc …