Extraislet expression of islet antigen boosts T cell exhaustion to partially prevent autoimmune diabetes
C Selck, G Jhala, DJ De George… - Proceedings of the …, 2024 - National Acad Sciences
Persistent antigen exposure results in the differentiation of functionally impaired, also termed
exhausted, T cells which are maintained by a distinct population of precursors of exhausted …
exhausted, T cells which are maintained by a distinct population of precursors of exhausted …
Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule
Summary Glucagon-like peptide-1 receptor (GLP-1R) is a key regulator of glucose
metabolism known to be expressed by pancreatic β cells. We herein investigated the role of …
metabolism known to be expressed by pancreatic β cells. We herein investigated the role of …
[PDF][PDF] fPCe=> ress Cell Metabolism
SUMMARY Glucagon-like peptide-1 receptor (GLP-1R) is a key regulator of glucose
metabolism known to be expressed by pancreatic b cells. We herein investigated the role of …
metabolism known to be expressed by pancreatic b cells. We herein investigated the role of …
Pathogenic role of different phenotypes of immune cells in airway allergic diseases: a study based on Mendelian randomization
Z Xu, R Li, L Wang, Y Wu, Y Tian, Y Su, Y Ma… - Frontiers in …, 2024 - frontiersin.org
Background Airway allergic disease (AAD) is a class of autoimmune diseases with
predominantly Th2-type inflammation, mainly including allergic rhinitis (AR), allergic asthma …
predominantly Th2-type inflammation, mainly including allergic rhinitis (AR), allergic asthma …
Is there a causal association between gestational diabetes mellitus and immune mediators? A bidirectional Mendelian randomization analysis
Z Ji, C Zhang, J Yuan, Q He, X Zhang… - Frontiers in …, 2024 - frontiersin.org
Background Diabetes that only appears or is diagnosed during pregnancy is referred to as
gestational diabetes mellitus (GDM). The maternal physiological immune profile is essential …
gestational diabetes mellitus (GDM). The maternal physiological immune profile is essential …