Background Near-patient testing has made self-monitoring of anticoagulation with warfarin
feasible, and several trials have suggested that such monitoring might be equal to or better …

Learning Objectives Cite the current indications, basic clinical pharmacology, and rationale
for development of the new oral anticoagulants. Explain the potential risk for drug-drug …

Background and Purpose—Warfarin is the most effective stroke prevention medication for
high-risk individuals with atrial fibrillation, yet it is often underused. This study examined the …

Background: Practice guidelines recommend long‐term stroke prophylaxis in patients with
chronic atrial fibrillation (cAF). Objectives: To examine treatment initiation and persistence …

Atrial fibrillation (AF) is the most common significant cardiac rhythm disorder. Oral
anticoagulation (OAC) is recommended by guidelines in the presence of a moderate to high …

Health care in Sub-Saharan Africa is being challenged by a double burden of disease as
lifestyle diseases common in the developed world, such as stroke and atrial fibrillation (AF) …

Background Trials show that oral anticoagulation therapy (OAT) substantially reduces
thromboembolic events without an increase in major haemorrhagic events, but it is not …

Background Patients with nonvalvular atrial fibrillation (NVAF) are at increased risk for stroke
and bleeding events, but bleeding as an outcome has not been extensively studied in this …

Anticoagulation (AC) is effective in reducing thromboembolic events for individuals with
atrial fibrillation (AF) or mechanical heart valve (MHV), but maintaining patients in target …

Despite overwhelming evidence of the benefits of risk-adjusted oral anticoagulation on
stroke reduction in patients with atrial fibrillation (AF), there is still considerable …