Cytokines: from clinical significance to quantification

C Liu, D Chu, K Kalantar‐Zadeh, J George… - Advanced …, 2021 - Wiley Online Library
Cytokines are critical mediators that oversee and regulate immune and inflammatory
responses via complex networks and serve as biomarkers for many diseases. Quantification …

Sickness behaviors across vertebrate taxa: proximate and ultimate mechanisms

PC Lopes, SS French… - Journal of …, 2021 - journals.biologists.com
There is nothing like a pandemic to get the world thinking about how infectious diseases
affect individual behavior. In this respect, sick animals can behave in ways that are …

The reptilian perspective on vertebrate immunity: 10 years of progress

LM Zimmerman - Journal of Experimental Biology, 2020 - journals.biologists.com
Ten years ago,'Understanding the vertebrate immune system: insights from the reptilian
perspective'was published. At the time, our understanding of the reptilian immune system …

The untapped potential of reptile biodiversity for understanding how and why animals age

LA Hoekstra, TS Schwartz, AM Sparkman… - Functional …, 2020 - Wiley Online Library
The field of comparative ageing biology has greatly expanded in the past 20 years.
Longitudinal studies of populations of reptiles with a range of maximum lifespans have …

Adaptive immunity in reptiles: Conventional components but unconventional strategies

LM Zimmerman - Integrative and Comparative Biology, 2022 - academic.oup.com
Recent studies have established that the innate immune system of reptiles is broad and
robust, but the question remains: What role does the reptilian adaptive immune system play …

Time course of splenic cytokine mRNA and hormones during a lipopolysaccharide-induced inflammation in toads

FR Floreste, B Titon Jr, SCM Titon… - Integrative and …, 2022 - academic.oup.com
Inflammation comprises alterations in glucocorticoids (in amphibians, corticosterone—
CORT) and melatonin (MEL) levels, two hormones with immunomodulatory effects on …

Liver vs. spleen: Time course of organ-dependent immune gene expression in an LPS-stimulated toad (Rhinella diptycha)

FR Floreste, B Titon Jr, SCM Titon, SM Muxel… - … and Physiology Part B …, 2023 - Elsevier
The inflammatory response comprises highly orchestrated events that are conserved
amongst vertebrate groups. Hepatic and splenic cytokines are major mediators of the …

Raloxifene improves TNF‑α‑induced osteogenic differentiation inhibition of bone marrow mesenchymal stem cells and alleviates osteoporosis

F Yang, Y Jia, Q Sun, C Zheng… - Experimental and …, 2020 - spandidos-publications.com
Abstract Effect of raloxifene (RLF) on the improvement of inhibited osteogenic differentiation
of bone marrow mesenchymal stem cells (BMSCs) resulted from tumor necrosis factor‑α …

Plasma antibacterial activities in ornate (Terrapene ornata) and eastern box turtles (Terrapene carolina)

L Adamovicz, SJ Baker, M Merchant… - … Zoology Part A …, 2020 - Wiley Online Library
Chelonians are one of the most imperiled vertebrate taxa and many species are increasingly
threatened by disease, however, the immune response in this group is understudied. We …

Temperature affects the host hematological and cytokine response following experimental ranavirus infection in red-eared sliders (Trachemys scripta elegans)

JM Rayl, MC Allender - Plos one, 2020 - journals.plos.org
Pathogen-host interactions are important components of epidemiological research, but are
scarcely investigated in chelonians. Red-eared sliders (Trachemys scripta elegans), are …