Sex differences in inflammation and muscle wasting in aging and disease
C Della Peruta, B Lozanoska-Ochser… - International journal of …, 2023 - mdpi.com
Only in recent years, thanks to a precision medicine-based approach, have treatments
tailored to the sex of each patient emerged in clinical trials. In this regard, both striated …
tailored to the sex of each patient emerged in clinical trials. In this regard, both striated …
Fiber-type traps: revisiting common misconceptions about skeletal muscle fiber types with application to motor control, biomechanics, physiology, and biology
SS Blemker, SV Brooks, KA Esser… - Journal of Applied …, 2024 - journals.physiology.org
Skeletal muscle is a highly complex tissue that is studied by scientists from a wide spectrum
of disciplines, including motor control, biomechanics, exercise science, physiology, cell …
of disciplines, including motor control, biomechanics, exercise science, physiology, cell …
Sex differences in endurance exercise capacity and skeletal muscle lipid metabolism in mice
LE Holcomb, P Rowe, CC O'Neill… - Physiological …, 2022 - Wiley Online Library
Previous studies suggest that sex differences in lipid metabolism exist with females
demonstrating a higher utilization of lipids during exercise, which is mediated partly by …
demonstrating a higher utilization of lipids during exercise, which is mediated partly by …
Skeletal muscle microvascular dysfunction in obesity-related insulin resistance: pathophysiological mechanisms and therapeutic perspectives
CK Ugwoke, E Cvetko, N Umek - International journal of molecular …, 2022 - mdpi.com
Obesity is a worrisomely escalating public health problem globally and one of the leading
causes of morbidity and mortality from noncommunicable disease. The epidemiological link …
causes of morbidity and mortality from noncommunicable disease. The epidemiological link …
Microvascular skeletal-muscle crosstalk in health and disease
GJ Pepe, ED Albrecht - International Journal of Molecular Sciences, 2023 - mdpi.com
As an organ system, skeletal muscle is essential for the generation of energy that underpins
muscle contraction, plays a critical role in controlling energy balance and insulin-dependent …
muscle contraction, plays a critical role in controlling energy balance and insulin-dependent …
Muscle miRNAs are influenced by sex at baseline and in response to exercise
Background Sex differences in microRNA (miRNA) expression profiles have been found
across multiple tissues. Skeletal muscle is one of the most sex-biased tissues of the body …
across multiple tissues. Skeletal muscle is one of the most sex-biased tissues of the body …
NMJ-related diseases beyond the congenital myasthenic syndromes
A Navarro-Martínez, C Vicente-García… - Frontiers in Cell and …, 2023 - frontiersin.org
Neuromuscular junctions (NMJs) are a special type of chemical synapse that transmits
electrical stimuli from motor neurons (MNs) to their innervating skeletal muscle to induce a …
electrical stimuli from motor neurons (MNs) to their innervating skeletal muscle to induce a …
Advances in Tissue Engineering Approaches for Repairing and Rehabilitating the Myotendinous Junction
KA Shama, MA Turner, HB Broadaway… - Current Opinion in …, 2024 - Elsevier
The myotendinous junction (MTJ) acts as a bridge between muscle and tendon; yet its high
stiffness relative to muscle fibers renders the tissue susceptible to injuries due to eccentric …
stiffness relative to muscle fibers renders the tissue susceptible to injuries due to eccentric …
Different responses of skeletal muscles to femoral artery ligation-induced ischemia identified in BABL/c and C57BL/6 mice
H Tu, J Qian, D Zhang, AN Barksdale… - Frontiers in …, 2022 - frontiersin.org
Peripheral arterial disease (PAD) is a common circulatory problem in lower extremities, and
the murine ischemic model is used to reproduce human PAD. To compare strain differences …
the murine ischemic model is used to reproduce human PAD. To compare strain differences …
Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia‐inducible factor‐1α in normoxia
Abstract Hypoxia‐inducible factor (HIF)‐1α is continuously synthesized and degraded in
normoxia. During hypoxia, HIF1α stabilization restricts cellular/mitochondrial oxygen …
normoxia. During hypoxia, HIF1α stabilization restricts cellular/mitochondrial oxygen …