Non-recurrent SEPT9 duplications cause hereditary neuralgic amyotrophy

AMB Collie, ML Landsverk, E Ruzzo… - Journal of medical …, 2010 - jmg.bmj.com
Background Genomic copy number variants have been shown to be responsible for multiple
genetic diseases. Recently, a duplication in septin 9 (SEPT9) was shown to be causal for …

[HTML][HTML] Septin 11 is present in GABAergic synapses and plays a functional role in the cytoarchitecture of neurons and GABAergic synaptic connectivity

X Li, DR Serwanski, CP Miralles, K Nagata… - Journal of Biological …, 2009 - ASBMB
Mass spectrometry and immunoblot analysis of a rat brain fraction enriched in type-II
postsynaptic densities and postsynaptic GABAergic markers showed enrichment in the …

Septin localization across kingdoms: three themes with variations

R Lindsey, M Momany - Current opinion in microbiology, 2006 - Elsevier
Septins are GTPases that form filaments in fungi and animals. In addition to their original
role in cell division, septins have been shown to have roles in coordinating nuclear division …

[HTML][HTML] SEPTIN12 Genetic Variants Confer Susceptibility to Teratozoospermia

YH Lin, YY Wang, HI Chen, YC Kuo, YW Chiou… - PLoS …, 2012 - journals.plos.org
It is estimated that 10–15% of couples are infertile and male factors account for about half of
these cases. With the advent of intracytoplasmic sperm injection (ICSI), many infertile men …

Turning it inside out: the organization of human septin heterooligomers

MA McMurray, J Thorner - Cytoskeleton, 2019 - Wiley Online Library
Septin family proteins are quite similar to each other both within and between eukaryotic
species. Typically, multiple discrete septins co‐assemble into linear heterooligomers …

Detection of colorectal cancer by DNA methylation biomarker SEPT9: past, present and future

Y Li, L Song, Y Gong, B He - Biomarkers in medicine, 2014 - Taylor & Francis
Colorectal cancer has become the third most common cancer in the world. Early diagnosis
and treatment can significantly reduce colorectal cancer mortality. The current routinely used …

Functional characterization of septin complexes

KA Akhmetova, IN Chesnokov, SA Fedorova - Molecular Biology, 2018 - Springer
Septins belong to a family of conserved GTP-binding proteins found in majority of eukaryotic
species except for higher plants. Septins form nonpolar complexes that further polymerize …

A simple method for GFP-and RFP-based dual color single-molecule localization microscopy

E Platonova, CM Winterflood, H Ewers - ACS chemical biology, 2015 - ACS Publications
The recent development of single-molecule localization-based super-resolution techniques
has afforded a resolution in the nanometer range in light microscopy. The ability to resolve …

[HTML][HTML] A Loss of Function Analysis of Host Factors Influencing Vaccinia virus Replication by RNA Interference

PM Beard, SJ Griffiths, O Gonzalez, IR Haga… - PLoS …, 2014 - journals.plos.org
Vaccinia virus (VACV) is a large, cytoplasmic, double-stranded DNA virus that requires
complex interactions with host proteins in order to replicate. To explore these interactions a …

The septin cytoskeleton in myelinating glia

AM Buser, B Erne, HB Werner, KA Nave… - Molecular and Cellular …, 2009 - Elsevier
Myelin is organized in subdomains with distinct protein and lipid composition. How these
domains are established and maintained is currently unknown. Cytoskeletal elements …