Septins embrace a large family of proteins highly conserved among eukaryotic species.
They were originally identified in budding yeast in the early 1970s as proteins essential for …

The conserved septin family of filamentous small GTPases plays important roles in mitosis,
cell migration and cell morphogenesis by forming scaffolds and diffusion barriers. Recent …

The purpose of this work was to determine SEPT9_v1 expression levels in head and neck
squamous cell carcinoma (HNSCC) and to analyze whether SEPT9_v1 expression is …

Forchlorfenuron (FCF) is a synthetic plant cytokinin that has been shown to alter yeast and
mammalian septin organization. Septins are a highly conserved family of GTP-binding …

SEPT9 is a member of the cytoskeleton‐related septin family, which is highly expressed in
glia cells in neuronal tissues. Sequence alterations in SEPT9 are known to cause hereditary …

We describe the purification, crystallization and structure for the GTP-binding domain of
human septin 7 (SEPT7G). We show that it forms filaments within the crystal lattice which …

The budding yeast proteins Dma1 and Dma2 are members of the unique FHA-RING domain
protein family and are linked to mitotic regulation and septin organization by ill-defined …

Septin proteins are a subfamily of closely related GTP-binding proteins conserved in all
species except for higher plants and perform essential biological processes. Septins self …

Chronic kidney disease (CKD) is characterized by the loss of nephrons and worsening
organ‐fibrosis that leads to deterioration and ultimately the total breakdown of kidney …

Microglia play key immunological roles in the central nervous system. Upon activation,
resident microglial cells transform from a ramified form to an amoeboid form and acquire the …