Septins are cytoskeletal proteins conserved from algae and protists to mammals. Septin
knock-out animals have established that septins are essential for animal physiology, but …

Vinexin is an adaptor protein that is supposed to play pivotal roles in cell adhesion,
cytoskeletal organization and signaling. At least three splice variants, vinexinα, β and γ …

septin 是一个广泛存在于除植物以外所有真核生物中的基因家族. 最初认为septin
家族是与酵母细胞胞质分裂相关的基因家族. 然而随着研究的深入, 人们发现这类基因编码的 …

As a result of recurrent chromosomal translocations in acute leukemias, the mixed-lineage-
leukemia (MLL) gene fuses with a variety of partner genes, which include several members …

An increasing body of data implicates the Septin family in the pathology of several diseases,
including male fertility. The objective of this study was to evaluate the gene and protein …

Septin4 belong to a family of polymerizing GTP-binding proteins that are required for many
cellular functions, such as membrane compartmentalization, vesicular trafficking, mitosis …

The molecular mechanisms responsible for protein structural changes in the central nervous
system leading to Alzheimer's disease are unknown, but there is evidence that a family of …

Septins are a highly conserved family of GTPases which are identified in diverse organisms
ranging from yeast to humans. In mammals, nervous tissues abundantly contain septins and …

Among various effector proteins for the small GTPase Rho, the function (s) of Rhotekin is
(are) almost unknown. We have identified PIST [P DZ (P SD-95, D iscs-large and Z O-1) …

Septin forms a conserved family of cytoskeletal guanosine triphosphate (GTP) binding
proteins that have diverse roles in protein scaffolding, vesicle trafficking, and cytokinesis …