There is an increasing evidence linking dysbalance between various proinflammatory
mediators and higher risk of cardiovascular events and pathologies. Likewise, some of the …

Cardio vascular disease (CVD) is the end result of the accumulation of atheromatous
plaques within the walls of the coronary arteries and remains the leading cause of death …

BACKGROUND: The single-nucleotide polymorphisms (SNPs) of the phosphodiesterase 4D
(PDE4D) and interleukin-1 (IL-1) genes are associated with increased risk for the …

Background and Purpose—Evidence is emerging that inflammation plays a key role in the
pathophysiology of ischemic stroke (IS). The aim of this study was to investigate whether …

Background: Cytokines are a group of polypeptides with an important role in the
inflammatory response. It has been suggested that certain polymorphisms located in several …

В современном мире острые нарушения мозгового кровообращения (инсульты)
относятся к важнейшим медико-социальным проблемам, что обусловлено их высокой …

Many epidemiological studies have investigated the associations between polymorphisms
of interleukin-1 (IL1) and interleukin-6 (IL6) genes and risk of ischemic stroke (IS), but no …

Interleukin-1 (IL-1) is a cytokine involved in the maturation and proliferation of B cells and
plays a significant role in the development of lytic bone lesions, a major clinical feature of …

Cerebrovascular accidents (strokes) are a challenge to modern health care throughout the
world because they contribute greatly to morbidity, disability, and mortality rates. Ischemic …

Abstract Aim The association between Interleukin-1 (IL-1) gene polymorphism and stroke
remains controversial. The present study was designed to clarify this relationship through a …