Neurotrophic factors in the porcine ovary: Their effects on follicular growth, oocyte maturation, and developmental competence

M Kim, SH Hyun - Frontiers in Veterinary Science, 2022 - frontiersin.org
Pigs are cost-effective industrial animals because they produce a large number of offspring
and have shorter rebreeding intervals compared with other animals, such as non-human …

The potential roles of neurotrophins in male reproduction

C Li, X Zhou - Reproduction, 2013 - rep.bioscientifica.com
Neurotrophins are a family of polypeptide growth factors that are required for the
proliferation, differentiation, survival, and death of neuronal cells. A growing body of …

Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract

R Chow, JM Wessels, WG Foster - Human Reproduction Update, 2020 - academic.oup.com
BACKGROUND Neurotrophins of the nerve growth factor family are soluble polypeptides
that are best known for their role in nerve growth, survival and differentiation in the central …

Early bovine embryos regulate oviduct epithelial cell gene expression during in vitro co-culture

B Schmaltz-Panneau, A Cordova… - Animal Reproduction …, 2014 - Elsevier
In mammals, the oviduct may participate to the regulation of early embryo development. In
vitro co-culture of early bovine embryos with bovine oviduct epithelial cells (BOEC) has been …

Neurotrophin-4 promotes the specification of trophectoderm lineage after parthenogenetic activation and enhances porcine early embryonic development

M Kim, J Lee, L Cai, H Choi, D Oh, A Jawad… - Frontiers in Cell and …, 2023 - frontiersin.org
Neurotrophin-4 (NT-4), a neurotrophic factor, appears to affect early embryonic development
because it is secreted not only by neurons but also by oviductal and uterine epithelial cells …

The mechanisms of BDNF promoting the proliferation of porcine follicular granulosa cells: role of miR-127 and involvement of the MAPK-ERK1/2 pathway

X Zheng, L Chen, T Chen, M Cao, B Zhang, C Yuan… - Animals, 2023 - mdpi.com
Simple Summary Recently, increasing the efficiency of porcine embryo cultures by
promoting oocyte maturation in vitro has attracted much attention. Brain-derived …

Brain‐derived neurotrophic factor promotes proliferation and progesterone synthesis in bovine granulosa cells

S Chen, F Wang, Z Liu, Y Zhao, Y Jiang… - Journal of Cellular …, 2019 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is involved in regulating the growth of ovarian
follicles, maturation of the oocyte, and development of the early embryo through its receptor …

Beneficial Effects of Neurotrophin-4 Supplementation During in vitro Maturation of Porcine Cumulus-Oocyte Complexes and Subsequent Embryonic Development …

M Kim, SU Hwang, JD Yoon, J Lee, E Kim… - Frontiers in Veterinary …, 2021 - frontiersin.org
Neurotrophin-4 (NT-4) is a neurotrophic factor that plays an important role in follicular
development and oocyte maturation. However, it is not yet known whether NT-4 is related to …

BDNF-induced expansion of cumulus-oocyte complexes in pigs was mediated by microRNA-205

C Li, C Chen, L Chen, S Chen, H Li, Y Zhao, J Rao… - Theriogenology, 2016 - Elsevier
The neurotrophin family of proteins is required for the survival and differentiation of the
nervous system and is important to the development of reproductive tissues. The objectives …

Effect of brain‐derived neurotrophic factor on sperm function, oxidative stress and membrane integrity in human

A Najafi, F Amidi, MA Sedighi Gilani, AR Moawad… - Andrologia, 2017 - Wiley Online Library
Oxidative stress has negative impacts on the clinical outcomes of assisted reproduction
techniques. The brain‐derived neurotrophic factor (BDNF) promotes the viability of nerve …