[HTML][HTML] Clinical pharmacokinetics of gentamicin in various patient populations and consequences for optimal dosing for gram-negative infections: an updated review

CJ Hodiamont, AK van den Broek, SL de Vroom… - Clinical …, 2022 - Springer
Gentamicin is an aminoglycoside antibiotic with a small therapeutic window that is currently
used primarily as part of short-term empirical combination therapy. Gentamicin dosing …

[HTML][HTML] Individualising therapy to minimize bacterial multidrug resistance

AJ Heffernan, FB Sime, J Lipman, JA Roberts - Drugs, 2018 - Springer
The scourge of antibiotic resistance threatens modern healthcare delivery. A contributing
factor to this significant issue may be antibiotic dosing, whereby standard antibiotic regimens …

[HTML][HTML] Short-course aminoglycosides as adjunctive empirical therapy in patients with Gram-negative bloodstream infection, a cohort study

JWT Deelen, WC Rottier, AGM Buiting… - Clinical Microbiology …, 2021 - Elsevier
Objective Short-course aminoglycosides as adjunctive empirical therapy to β-lactams in
patients with a clinical suspicion of sepsis are used to broaden antibiotic susceptibility …

[HTML][HTML] Evaluation of aminoglycosides utilization in intensive care units of a teaching hospital in southern Iran

A Vazin, M Mirjalili, S Asadi - Pharmacy Practice (Granada), 2019 - SciELO Espana
Resumen VAZIN, Afsaneh; MIRJALILI, Mahtabalsadat y ASADI, Sara. Evaluation of
aminoglycosides utilization in intensive care units of a teaching hospital in southern Iran …

Re:'Is a randomized trial of a short course of aminoglycoside added to β-lactam antibiotics for empirical treatment in critically ill patients with sepsis justified?' …

A Heffernan, J Lipman… - Clinical …, 2018 - clinicalmicrobiologyandinfection …
We read with interest the comments from Ong et al.[1] regarding the need for a well-
designed randomized controlled trial (RCT) to provide evidence to guide clinicians …