[HTML][HTML] Nutrition, IBD and gut microbiota: a review

MC Mentella, F Scaldaferri, M Pizzoferrato… - Nutrients, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing–remitting systemic disease of the
gastrointestinal tract, characterized by an inflammatory process that requires lifelong …

Diet fuelling inflammatory bowel diseases: preclinical and clinical concepts

TE Adolph, J Zhang - Gut, 2022 - gut.bmj.com
The diet and gut microbiota have been extensively interrogated as a fuel for gut
inflammation in inflammatory bowel diseases (IBDs) in the last few years. Here, we review …

[HTML][HTML] MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice

AP Perera, R Fernando, T Shinde, R Gundamaraju… - Scientific reports, 2018 - nature.com
MCC950 a potent, highly specific small molecule inhibitor of canonical and noncanonical
activation of NLRP3 inflammasome has been evaluated in a multitude of NLRP3 driven …

Inflammatory bowel disease: clinical aspects and treatments

M Fakhoury, R Negrulj, A Mooranian… - Journal of inflammation …, 2014 - Taylor & Francis
Inflammatory bowel disease (IBD) is defined as a chronic intestinal inflammation that results
from host-microbial interactions in a genetically susceptible individual. IBDs are a group of …

Therapeutic potential of MCC950, a specific inhibitor of NLRP3 inflammasome

H Li, Y Guan, B Liang, P Ding, X Hou, W Wei… - European journal of …, 2022 - Elsevier
NOD-like receptor protein 3 (NLRP3), an important intracellular pattern recognition receptor,
is a component of the NLRP3 inflammasome along with apoptosis-associated speck-like …

The microbiota in inflammatory bowel disease: current and therapeutic insights

ER Lane, TL Zisman, DL Suskind - Journal of inflammation …, 2017 - Taylor & Francis
Inflammatory bowel disease is a heterogeneous group of chronic disorders that result from
the interaction of the intestinal immune system with the gut microbiome. Until recently, most …

Meta-analysis: fecal calprotectin for assessment of inflammatory bowel disease activity

JF Lin, JM Chen, JH Zuo, A Yu, ZJ Xiao… - Inflammatory bowel …, 2014 - academic.oup.com
Background Fecal calprotectin (FC) is a promising biomarker for diagnosis of inflammatory
bowel disease (IBD). However, the utility of FC for assessment of IBD activity has yet to be …

Association between inflammatory bowel disease and vitamin D deficiency: a systematic review and meta-analysis

R Del Pinto, D Pietropaoli, AK Chandar… - Inflammatory bowel …, 2015 - academic.oup.com
Background Vitamin D plays a role in several immune-mediated diseases, but its
association with inflammatory bowel disease (IBD) is unclear. We conducted a systematic …

[HTML][HTML] The epidemiology and risk factors of inflammatory bowel disease

Y Ye, Z Pang, W Chen, S Ju, C Zhou - International journal of …, 2015 - ncbi.nlm.nih.gov
This review aimed to summarize the epidemiology (incidence, prevalence and morality) and
risk factors of inflammatory bowel disease (IBD). IBD is a chronic, relapsing, inflammatory …

[HTML][HTML] Phytochemicals as anti-inflammatory agents in animal models of prevalent inflammatory diseases

SA Shin, BJ Joo, JS Lee, G Ryu, M Han, WY Kim… - Molecules, 2020 - mdpi.com
Phytochemicals are known to have anti-inflammatory effects in vitro and in vivo, such as in
inflammatory disease model systems. Inflammation is an essential immune response to …