[HTML][HTML] Immunotherapeutic approaches in Hepatocellular carcinoma: Building blocks of hope in near future

N Minaei, R Ramezankhani, A Tamimi, A Piryaei… - European Journal of …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is the most common type of primary hepatic cancer and is
among the major causes of mortality due to cancer. Due to the lack of efficient conventional …

Nanoparticles in the diagnosis and treatment of cancer metastases: Current and future perspectives

M Hegde, N Naliyadhara, J Unnikrishnan… - Cancer Letters, 2023 - Elsevier
Metastasis accounts for greater than 90% of cancer-related deaths. Despite recent
advancements in conventional chemotherapy, immunotherapy, targeted therapy, and their …

Advances in Immunotherapy for Hepatocellular Carcinoma (HCC)

F Bicer, C Kure, AA Ozluk, BF El-Rayes, M Akce - Current Oncology, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related
deaths in the world. More than half of patients with HCC present with advanced stage, and …

S100 proteins in fatty liver disease and hepatocellular carcinoma

E Delangre, E Oppliger, S Berkcan… - International journal of …, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent and slow progressing hepatic
pathology characterized by different stages of increasing severity which can ultimately give …

Radiomics models based on multisequence MRI for predicting PD-1/PD-L1 expression in hepatocellular carcinoma

XQ Gong, N Liu, YY Tao, L Li, ZM Li, L Yang… - Scientific Reports, 2023 - nature.com
The purpose of this study was to explore the effectiveness of radiomics based on
multisequence MRI in predicting the expression of PD-1/PD-L1 in hepatocellular carcinoma …

Targeting TRMT5 suppresses hepatocellular carcinoma progression via inhibiting the HIF-1α pathways

Q Zhao, L Zhang, Q He, H Chang, Z Wang… - Journal of Zhejiang …, 2023 - Springer
Accumulating evidence has confirmed the links between transfer RNA (tRNA) modifications
and tumor progression. The present study is the first to explore the role of tRNA …

Tertiary lymphoid structures: Associated multiple immune cells and analysis their formation in hepatocellular carcinoma

Y Nie, H Fan, J Li, X Lei, T Zhang, Y Wang… - The FASEB …, 2022 - Wiley Online Library
The prognostic value of immune cells in tertiary lymphoid structures (TLSs) remains unclear
in hepatocellular carcinoma (HCC). Here, 59 of 145 patients had TLSs in training set, 48 of …

Comprehensive Analysis of the Immune Infiltrates and PD-L1 of m6A RNA Methylation Regulators in Hepatocellular Carcinoma

Y Xu, X He, J Deng, L Xiong, Y Li, X Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
Recently, N 6-methyladenosine (m6A) RNA methylation in eukaryotic mRNA has become
increasingly obvious in the pathogenesis and prognosis of cancer. Moreover, tumor …

Regulator of G protein signaling 20 correlates with long intergenic non-coding rna (Lincrnas) harboring oncogenic potential and is markedly upregulated in …

Y Wang, MF Setiawan, H Liu, TC Dakal, H Liu, F Ge… - Biology, 2022 - mdpi.com
Simple Summary Clinical and molecular advances have improved knowledge and treatment
prospects for cancer, yet hepatocellular carcinoma (HCC), the most common form of liver …

Primary resistance to immunotherapy-based regimens in first line hepatocellular carcinoma: perspectives on jumping the hurdle

F Salani, V Genovesi, C Vivaldi, V Massa, S Cesario… - Cancers, 2022 - mdpi.com
Simple Summary Immune checkpoint inhibitors (ICIs) had been explored extensively in
patients affected by unresectable hepatocellular carcinoma. These agents were expected to …