The immune system plays a pivotal role in combating diseases, including cancer, with
monocytes emerging as key regulators of immune response dynamics. This article describes …

The effect of recombinant alpha-fetoprotein (AFP) on human myeloid suppressor cell
(MDSC) differentiation was studied in vitro in the presence of cytokines IL-6 (10 ng/mL) and …

Discussion Apoptosis erases the cells with unrepairable mutations. Irradiation and some
chemotherapies are used to generate those mutations in cancer cells. They expect the …

One in two people will be diagnosed with cancer in their lifetime in developed countries.
Prophylactics and early diagnostics are recommended to everyone. On the other hand, even …

Cancer disease results from mutations leading to apoptosis failure and immune system
dysfunction. Because one in two people in developed counties will be diagnosed with …

The inefficiency of the immune system to kill cancer cells leads to the disease. Like in
pregnancy, oncofetal proteins counteract the immune attack. Alpha-fetoprotein is an …

Oncofetal alpha-fetoprotein (AFP) activates in developing as well as in growing cancer cells.
It delivers polyunsaturated fatty acids through specific cell receptors. AFP-binding receptors …

Alpha-fetoprotein (AFP) delivers ligands to monocytes/macrophages that regulate the
immune system activity. AFP or AFP-drugs can be used to treat autoimmune diseases, while …