Aging of mesenchymal stem cell: machinery, markers, and strategies of fighting

M Al-Azab, M Safi, E Idiiatullina, F Al-Shaebi… - Cellular & Molecular …, 2022 - Springer
Human mesenchymal stem cells (MSCs) are primary multipotent cells capable of
differentiating into osteocytes, chondrocytes, and adipocytes when stimulated under …

Superoxide release by macrophages through NADPH oxidase activation dominating chemistry by isoprene secondary organic aerosols and quinones to cause …

T Fang, YK Huang, J Wei… - … science & technology, 2022 - ACS Publications
Oxidative stress mediated by reactive oxygen species (ROS) is a key process for adverse
aerosol health effects. Secondary organic aerosols (SOA) account for a major fraction of fine …

Rutin attenuates D-galactose-induced oxidative stress in rats' brain and liver: molecular docking and experimental approaches

SM Saafan, SA Mohamed, AE Noreldin… - Food & Function, 2023 - pubs.rsc.org
Oxidative stress results from the imbalance between reactive oxygen species (ROS)
production and antioxidant defence and is primarily involved in aging. The current study …

Sevoflurane increases intracellular calcium to induce mitochondrial injury and neuroapoptosis

X Zhu, Y Yao, M Guo, J Li, P Yang, H Xu, D Lin - Toxicology letters, 2021 - Elsevier
Sevoflurane is commonly used in clinical anesthesia. However, some reports indicated that
Sevoflurane could induce mitochondrial injury and neuroapoptosis. Although the …

Alginate oligosaccharide alleviates D‐galactose‐induced cardiac ageing via regulating myocardial mitochondria function and integrity in mice

W Feng, J Liu, S Wang, Y Hu, H Pan… - Journal of Cellular …, 2021 - Wiley Online Library
Ageing is a crucial risk factor for the development of age‐related cardiovascular diseases.
Therefore, the molecular mechanisms of ageing and novel anti‐ageing interventions need to …

d-Galactose-induced oxidative stress and mitochondrial dysfunction in the cochlear basilar membrane: an in vitro aging model

B Guo, Q Guo, Z Wang, JB Shao, K Liu, ZD Du… - Biogerontology, 2020 - Springer
The cochlear basilar membrane (CBM) contains inner hair cells and outer hair cells that
convert sound waves into electrical signals and transmit them to the central auditory system …

ROS‐Induced Oxidative Damage and Mitochondrial Dysfunction Mediated by Inhibition of SIRT3 in Cultured Cochlear Cells

L Zhang, Z Du, L He, W Liang, K Liu, S Gong - Neural Plasticity, 2022 - Wiley Online Library
Sensorineural hearing loss (SNHL) is one of the most common causes of disability
worldwide. Previous evidence suggests that reactive oxygen species (ROS) may play an …

Preventive effect of cocoa flavonoids via suppression of oxidative stress-induced apoptosis in auditory senescent cells

L del Mar Rivas-Chacón, J Yanes-Díaz, B de Lucas… - Antioxidants, 2022 - mdpi.com
Presbycusis or Age-related hearing loss (ARHL) is a sensorineural hearing loss that affects
communication, leading to depression and social isolation. Currently, there are no effective …

Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats

J Hao, Y Xi, L Jiao, X Wen, R Wu, G Chang, F Sun… - Cellular signalling, 2022 - Elsevier
Abstract Hydrogen sulfide (H 2 S), a gaseous molecule, has been shown to be involved in
the regulation of body pathophysiological processes. Aging is related to structural and …

[HTML][HTML] ROS-induced oxidative stress and mitochondrial dysfunction: a possible mechanism responsible for noise-induced ribbon synaptic damage

ZJ Yang, CL Zhao, WQ Liang, ZR Chen… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Evidence suggests that damage to the ribbon synapses (RS) may be the main cause of
auditory dysfunction in noise-induced hearing loss (NIHL). Oxidative stress is implicated in …