Revisiting preeclampsia: a metabolic disorder of the placenta
Preeclampsia (PE) is a leading cause of maternal and neonatal mortality and morbidity
worldwide, impacting the long‐term health of both mother and offspring. PE has long been …
worldwide, impacting the long‐term health of both mother and offspring. PE has long been …
Placental nutrient transport in gestational diabetic pregnancies
M Castillo-Castrejon, TL Powell - Frontiers in endocrinology, 2017 - frontiersin.org
Maternal obesity during pregnancy is rising and is associated with increased risk of
developing gestational diabetes mellitus (GDM), defined as glucose intolerance first …
developing gestational diabetes mellitus (GDM), defined as glucose intolerance first …
Whole transcriptome expression profiles in placenta samples from women with gestational diabetes mellitus
L Tang, P Li, L Li - Journal of diabetes investigation, 2020 - Wiley Online Library
Abstract Aims/Introduction Non‐coding ribonucleic acids (ncRNAs) have recently been
shown to be involved in various biological processes. However, most of these ncRNAs are …
shown to be involved in various biological processes. However, most of these ncRNAs are …
Role of insulin in placental transport of nutrients in gestational diabetes mellitus
M Ruiz-Palacios, AJ Ruiz-Alcaraz… - Annals of Nutrition and …, 2017 - karger.com
Background: Gestational diabetes mellitus (GDM) is associated with increased fetal
adiposity, which may increase the risk of obesity in adulthood. The placenta has insulin …
adiposity, which may increase the risk of obesity in adulthood. The placenta has insulin …
Placental fatty acid transfer
Placental lipid metabolism is likely to be a determinant of placental transfer of fatty acids to
the fetus. Maternal conditions, such as obesity, have now been shown to regulate placental …
the fetus. Maternal conditions, such as obesity, have now been shown to regulate placental …
The Role of Gut Microbiota in Gestational Diabetes Mellitus Affecting Intergenerational Glucose Metabolism: Possible Mechanisms and Interventions
Y Ren, Y Zeng, Y Wu, J Yu, Q Zhang, X Xiao - Nutrients, 2023 - mdpi.com
The incidence of type 2 diabetes is increasing every year and has become a serious public
health problem. In addition to genetic factors, environmental factors in early life development …
health problem. In addition to genetic factors, environmental factors in early life development …
[HTML][HTML] Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity
AK Anam, KM Cooke, MB Dratver, JV O'Bryan… - Molecular …, 2022 - Elsevier
Objective Maternal obesity increases the incidence of excess adiposity in newborns,
resulting in lifelong diabetes risk. Elevated intrauterine fetal adiposity has been attributed to …
resulting in lifelong diabetes risk. Elevated intrauterine fetal adiposity has been attributed to …
Distribution of fatty acids and lipids during pregnancy
P Chavan-Gautam, A Rani, DJ Freeman - Advances in clinical chemistry, 2018 - Elsevier
Maternal fatty acid and lipid metabolism undergoes changes during pregnancy to facilitate
fetal growth and development. Different types of fatty acids have different roles in …
fetal growth and development. Different types of fatty acids have different roles in …
Placental lipid transport and content in response to maternal overweight and gestational diabetes mellitus in human term placenta
L Song, N Wang, Y Peng, B Sun, W Cui - Nutrition, Metabolism and …, 2022 - Elsevier
Background and aims Placental lipid transport is altered in women with high prepregnancy
body mass index (pre-BMI) or gestational diabetes (GDM), which consequently affects foetal …
body mass index (pre-BMI) or gestational diabetes (GDM), which consequently affects foetal …
Nutritional and developmental programming effects of insulin
The discovery of insulin in 1921 was a major breakthrough in medicine and for therapy in
patients with diabetes. The dramatic rise in the prevalence of overweight and obesity has …
patients with diabetes. The dramatic rise in the prevalence of overweight and obesity has …