Inborn errors of metabolism (IEM) are a phenotypically and genetically heterogeneous
group of disorders caused by a defect in a metabolic pathway, leading to malfunctioning …

Background Increasingly, vaccine efficacy studies are being recommended in low-and-
middle-income countries (LMIC), yet often facilities are unavailable to take and store infant …

Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal
health. In genome-wide association meta-analysis of European and Central Asian mothers …

Abstract The Integrative Psychiatric Research (iPSYCH) consortium has established a large
Danish population-based Case–Cohort sample (iPSYCH2012) aimed at unravelling the …

Asthma exacerbations are among the most frequent causes of hospitalization during
childhood, but the underlying mechanisms are poorly understood. We performed a genome …

There is mounting evidence that seemingly diverse psychiatric disorders share genetic
etiology, but the biological substrates mediating this overlap are not well characterized. Here …

Autism affects males more than females, giving rise to the idea that the influence of steroid
hormones on early fetal brain development may be one important early biological risk factor …

Importance Anxiety and stress-related disorders are among the most common mental
disorders. Although family and twin studies indicate that both genetic and environmental …

Importance Schizophrenia has a complex etiology influenced both by genetic and
nongenetic factors but disentangling these factors is difficult. Objective To estimate (1) how …

Context Clues from the epidemiology of schizophrenia suggest that low levels of
developmental vitamin D may be associated with increased risk of schizophrenia. Objective …