[HTML][HTML] High-quality exome sequencing of whole-genome amplified neonatal dried blood spot DNA

JB Poulsen, F Lescai, J Grove, M Bækvad-Hansen… - PloS one, 2016 - journals.plos.org
Stored neonatal dried blood spot (DBS) samples from neonatal screening programmes are
a valuable diagnostic and research resource. Combined with information from national …

Neonatal vitamin D levels and cognitive ability in young adulthood

IO Specht, J Janbek, F Thorsteinsdottir… - European journal of …, 2020 - Springer
Purpose Intelligence has a strong influence on life capability, and thus, identifying early
modifiable risk factors related to cognitive ability is of major public health interest. During …

[HTML][HTML] International differences in the evaluation of conditions for newborn bloodspot screening: a review of scientific literature and policy documents

ME Jansen, SC Metternick-Jones… - European Journal of …, 2017 - nature.com
Despite international adoption of newborn bloodspot screening (DBS), no two countries'
screening programs are the same. This article aims to understand what factors influence …

[HTML][HTML] The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders

N Borbye-Lorenzen, Z Zhu, E Agerbo, C Albiñana… - Cell genomics, 2023 - cell.com
Complement components have been linked to schizophrenia and autoimmune disorders.
We examined the association between neonatal circulating C3 and C4 protein …

[HTML][HTML] Neonatal vitamin D status and risk of asthma in childhood: results from the D-Tect study

F Thorsteinsdottir, I Cardoso, A Keller, M Stougaard… - Nutrients, 2020 - mdpi.com
Background: low vitamin D status in pregnancy can influence the offspring's lung function
and contribute to childhood asthma development. The objective of this study was to examine …

Metabolomics and adductomics of newborn bloodspots to retrospectively assess the early-life exposome

LM Petrick, K Uppal, WE Funk - Current opinion in pediatrics, 2020 - journals.lww.com
Adductomics and metabolomics of DBS can provide robust measurements for retrospective
epidemiological investigations. With extensive bioarchiving programs in the United States …

Schizophrenia polygenic risk scores, urbanicity and treatment-resistant schizophrenia

C Gasse, T Wimberley, Y Wang, O Mors… - Schizophrenia …, 2019 - Elsevier
Introduction To investigate the impact of a polygenic risk score for schizophrenia (PRS-SZ)
and urbanicity on the risk of treatment-resistant schizophrenia (TRS) in people diagnosed …

Gestational age-dependent development of the neonatal metabolome

M Ernst, S Rogers, U Lausten-Thomsen… - Pediatric …, 2021 - nature.com
Background Prematurity is a severe pathophysiological condition, however, little is known
about the gestational age-dependent development of the neonatal metabolome. Methods …

[HTML][HTML] Neonatal vitamin D status from archived dried blood spots and future risk of fractures in childhood: results from the D-tect study, a population-based case …

MN Händel, P Frederiksen, A Cohen, C Cooper… - The American journal of …, 2017 - Elsevier
Background: Whether antenatal and neonatal vitamin D status have clinical relevance in
fracture prevention has not been examined extensively, although observational studies …

Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders–findings from a Danish population-based study

X Liu, R Nudel, WK Thompson, V Appadurai… - Brain, behavior, and …, 2021 - Elsevier
Background Previous studies have indicated the bidirectionality between autoimmune and
mental disorders. However, genetic studies underpinning the co-occurrence of the two …