A novel pharmaceutical preparation of Tripterygium wilfordii Hook. f. regulates macrophage polarization to alleviate inflammation in rheumatoid arthritis

L Wan, J Liu, C Huang, K Wang… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives To validate the enhanced therapeutic effect of Tripterygium wilfordii Hook.
f.(TWHF) in the treatment of rheumatoid arthritis (RA) by restoring homeostasis of M1/M2 …

Exploring potential therapeutic agents for lipopolysaccharide-induced septic cardiomyopathy based on transcriptomics using bioinformatics

S Feng, K Cai, S Lin, X Chen, Y Luo, J Wang, G Lian… - Scientific Reports, 2023 - nature.com
Septic cardiomyopathy (SCM) is a common and severe complication of sepsis,
characterized by left ventricular dilation and reduced ejection fraction leading to heart …

Identification of differentially methylated genes for severe acne by genome-wide DNA methylation and gene expression analysis

H Wang, T Dang, J Feng, W Wu, L He, J Yang - Epigenetics, 2023 - Taylor & Francis
Severe acne is a chronic inflammatory skin condition that is affected by both genetic and
environmental factors. DNA methylation is associated with a variety of inflammatory skin …

Sepsis induced cardiotoxicity by promoting cardiomyocyte cuproptosis

J Yan, Z Li, Y Li, Y Zhang - Biochemical and Biophysical Research …, 2024 - Elsevier
Background Currently, sepsis induced cardiotoxicity is among the major causes of sepsis-
related death. The specific molecular mechanisms of sepsis induced cardiotoxicity are …

Scutellarein ameliorates inflammation and oxidative stress in L-arginine induced acute pancreatitis in mice through regulating the expression of VEGF

H Dong, W Ying, S Zhu - Molecular & Cellular Toxicology, 2023 - Springer
Background Acute pancreatitis (AP) is an abdominal disease mainly characterized by
oxidative stress and inflammation of the pancreas. Studies have reported that scutellarein …

Diagnostic model constructed by five EMT-related genes for renal fibrosis and reflecting the condition of immune-related cells

Y Guo, Z Yuan, Z Hu, Y Gao, H Guo, H Zhu… - Frontiers in …, 2023 - frontiersin.org
Background Renal fibrosis is a physiological and pathological characteristic of chronic
kidney disease (CKD) to end-stage renal disease. Since renal biopsy is the gold standard …