Comment on “Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics”

H Hólm, P Sulem, V Tragante… - Science Translational …, 2021 - science.org
Comment on “Evaluating the cardiovascular safety of sclerostin inhibition using evidence from
meta-analysis of clinical trials and human genetics” | Science Translational Medicine news …

Ancestral diversity in lipoprotein (a) studies helps address evidence gaps

MP Lee, SF Dimos, LM Raffield, Z Wang, AF Ballou… - Open …, 2023 - openheart.bmj.com
Introduction The independent and causal cardiovascular disease risk factor lipoprotein
(a)(Lp (a)) is elevated in> 1.5 billion individuals worldwide, but studies have prioritised …

Impact of lipoprotein (a) level on cardiometabolic disease in the Chinese population: The CHCN‐BTH Study

J Xia, C Guo, H Cao, K Liu, W Peng… - European Journal of …, 2022 - Wiley Online Library
Background The emergence of promising compounds to lower lipoprotein (a)[Lp (a)] has
increased the need for a precise characterisation and comparability assessment of Lp (a) …

[HTML][HTML] Lipoprotein (a) in an adult sample from the Russian population: distribution and association with atherosclerotic cardiovascular diseases

MV Ezhov, SA Shalnova, EB Yarovaya… - Archives of Medical …, 2023 - ncbi.nlm.nih.gov
Results The prevalence of Lp (a)≥ 30 mg/dl was 20.5% and 23.0%, and prevalence of Lp
(a)≥ 50 mg/dl was 13.3% and 15.2%, in men and women, respectively. An association of Lp …

[HTML][HTML] Lipoprotein (a) and the risk for recurrent atherosclerotic cardiovascular events among adults with CKD: the chronic renal insufficiency cohort (CRIC) study

B Poudel, RS Rosenson, ST Kent, V Bittner… - Kidney Medicine, 2023 - Elsevier
Rationale & Objective Many adults with chronic kidney disease (CKD) and atherosclerotic
cardiovascular disease (ASCVD) have high lipoprotein (a) levels. It is unclear whether high …

Lipoprotein (a) and cardiovascular disease prevention across diverse populations

K Pearson, F Rodriguez - Cardiology and Therapy, 2020 - Springer
Abstract Lipoprotein (a)(Lp (a)) is a highly proatherogenic lipid fraction that is genetically
determined and minimally responsive to lifestyle or behavior changes. Mendelian …

Relationship between lipoprotein (a) and colorectal cancer among inpatients: a retrospective study

H Wang, H Zheng, P Meng, X Cao, J Liu… - Frontiers in …, 2023 - frontiersin.org
The present study was to explore the association between lipoprotein (a)[Lp (a)] and
colorectal cancer (CRC) among inpatients. This study included 2822 participants (393 cases …

Association between lipoprotein (a) and risk of atherosclerotic cardiovascular disease events among maintenance hemodialysis patients in Beijing, China: a single …

Q Liang, G Zhang, L Jiang - BMC nephrology, 2024 - Springer
Abstract Background Serum lipoprotein (a)[Lp (a)] is an independent risk factor for
atherosclerotic cardiovascular disease (ASCVD) in the general population, its association …

Genetics of lipoprotein (a): cardiovascular disease and future therapy

A Langsted, BG Nordestgaard - Current Atherosclerosis Reports, 2021 - Springer
Abstract Purpose of Review Lipoprotein (a) levels are determined 80–90% by genetics and
differ by up to 1000-fold between individuals. This review discusses the most recent …

[HTML][HTML] Role of Glucose and Lipids in the Atherosclerotic Cardiovascular Disease in Patients with Diabetes

KR Feingold - 2015 - europepmc.org
Atherosclerotic cardiovascular disease (ASCVD) is a major cause of morbidity and mortality
in both men and women with T1DM and T2DM. In patients with T1DM, intensive glycemic …