[HTML][HTML] A concise review of mushrooms antiviral and immunomodulatory properties that may combat against COVID-19

K Arunachalam, SP Sasidharan, X Yang - Food Chemistry Advances, 2022 - Elsevier
Abstract The World Health Organization (WHO) declared COVID-19 as a pandemic on
March 11, 2020, because of its widespread transmission and infection rates. The unique …

[HTML][HTML] Therapeutic dilemmas in addressing SARS-CoV-2 infection: Favipiravir versus Remdesivir

PA Negru, AF Radu, CM Vesa, T Behl… - Biomedicine & …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) represents an unmet clinical need, due to a
high mortality rate, rapid mutation rate in the virus, increased chances of reinfection, lack of …

Obesity and COVID-19: mechanistic insights from adipose tissue

L Yu, X Zhang, S Ye, H Lian, H Wang… - The Journal of Clinical …, 2022 - academic.oup.com
Obesity is associated with an increase in morbidity and mortality from coronavirus disease
2019 (COVID-19). The risk is related to the cytokine storm, a major contributor to multiorgan …

[HTML][HTML] Economic evaluation of COVID-19 vaccination: A systematic review

AM Utami, F Rendrayani, QA Khoiry… - Journal of global …, 2023 - ncbi.nlm.nih.gov
Background Safe and effective vaccination is considered to be the most critical strategy to
fight coronavirus disease 2019 (COVID-19), leading to individual and herd immunity …

Real-world experience of the comparative effectiveness and safety of molnupiravir and nirmatrelvir/ritonavir in high-risk patients with COVID-19 in a community setting

Y Mutoh, T Umemura, T Nishikawa, K Kondo, Y Nishina… - Viruses, 2023 - mdpi.com
Molnupiravir (MOV) and nirmatrelvir/ritonavir (NMV/r) are efficacious oral antiviral agents for
patients with the 2019 coronavirus (COVID-19). However, little is known about their …

Discovery of small molecules targeting the frameshifting element RNA in SARS-CoV-2 viral genome

M Yang, FP Olatunji, C Rhodes… - ACS Medicinal …, 2023 - ACS Publications
Targeting structured RNA elements in the SARS-CoV-2 viral genome with small molecules
is an attractive strategy for pharmacological control over viral replication. In this work, we …

The potential of nanobodies for COVID-19 diagnostics and therapeutics

DB Naidoo, AA Chuturgoon - Molecular Diagnosis & Therapy, 2023 - Springer
The infectious severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the
causative agent for coronavirus disease 2019 (COVID-19). Globally, there have been …

Targeting the complement–sphingolipid system in COVID-19 and gaucher diseases: evidence for a new treatment strategy

VS Trivedi, AF Magnusen, R Rani, L Marsili… - International Journal of …, 2022 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-induced disease
(COVID-19) and Gaucher disease (GD) exhibit upregulation of complement 5a (C5a) and its …

A review on drug repurposing in COVID-19: from antiviral drugs to herbal alternatives

A Sezer, M Halilović-Alihodžić, AR Vanwieren… - Journal of Genetic …, 2022 - Springer
Background COVID-19 is an illness caused by severe acute respiratory syndrome
coronavirus 2. Due to its rapid spread, in March 2020 the World Health Organization (WHO) …

[HTML][HTML] Potential limitations in systematic review studies assessing the effect of the main intervention for treatment/therapy of COVID-19 patients: an overview

M Mohseni, H Ameri, M Arab-Zozani - Frontiers in Medicine, 2022 - frontiersin.org
Background Although several studies have assessed the safety, efficacy, and effectiveness
of interventions in treating the COVID-19, many of them have limitations that can have an …