Current research topics in FAPI theranostics: a bibliometric analysis

AF van den Hoven, RGM Keijsers, MGEH Lam… - European Journal of …, 2023 - Springer
Purpose The study aimed to provide a comprehensive bibliometric overview of the current
scientific publications on fibroblast activation protein inhibitor (FAPI) positron emission …

Theranostics in targeting fibroblast activation protein bearing cells: progress and challenges

S Rezaei, E Gharapapagh, S Dabiri, P Heidari… - Life Sciences, 2023 - Elsevier
Cancer cells are surrounded by a complex and highly dynamic tumor microenvironment
(TME). Cancer-associated fibroblasts (CAFs), a critical component of TME, contribute to …

One-stop [18F]FDG and [68Ga]Ga-DOTA-FAPI-04 total-body PET/CT examination with dual-low activity: a feasibility study

G Liu, W Mao, H Yu, Y Hu, J Gu, H Shi - European Journal of Nuclear …, 2023 - Springer
Purpose Positron emission tomography/computed tomography (PET/CT) based on fibroblast
activation protein inhibitors (FAPI) has shown complementary values to 2-[18F]-fluoro-2 …

From Automated Synthesis to In Vivo Application in Multiple Types of Cancer—Clinical Results with [68Ga]Ga-DATA5m.SA.FAPi

L Greifenstein, CS Kramer, ES Moon, F Rösch… - Pharmaceuticals, 2022 - mdpi.com
Radiolabeled FAPI (fibroblast activation protein inhibitors) recently gained attention as
widely applicable imaging and potential therapeutic compounds targeting CAF (cancer …

[HTML][HTML] First clinical experience with [68Ga] Ga-FAPI-46-PET/CT versus [18F] F-FDG PET/CT for nodal staging in cervical cancer

S Wegen, KS Roth, J Weindler, K Claus… - Clinical Nuclear …, 2023 - journals.lww.com
All procedures performed in studies involving human participants were in accordance with
the ethical standards of the institutional and/or national research committee and with the …

Development of an 18F-labeled anti-human CD8 VHH for same-day immunoPET imaging

SK Sriraman, CW Davies, H Gill, JR Kiefer, J Yin… - European Journal of …, 2023 - Springer
Abstract Purpose Cancer immunotherapies (CITs) have revolutionized the treatment of
certain cancers, but many patients fail to respond or relapse from current therapies …

From basic research to clinical application: targeting fibroblast activation protein for cancer diagnosis and treatment

Z Zhang, J Tao, J Qiu, Z Cao, H Huang, J Xiao… - Cellular Oncology, 2024 - Springer
Purpose This study aims to review the multifaceted roles of a membrane protein named
Fibroblast Activation Protein (FAP) expressed in tumor tissue, including its molecular …

Impact of FAPI-46/dual-tracer PET/CT imaging on radiotherapeutic management in esophageal cancer

S Wegen, K Claus, P Linde, J Rosenbrock… - Radiation …, 2024 - Springer
Background Fibroblast activation protein (FAP) is expressed in the tumor microenvironment
(TME) of various cancers. In our analysis, we describe the impact of dual-tracer imaging with …

Dual-tracer PET/CT protocol with [18F]FDG and [68Ga]Ga-FAPI-46 outperforms single-tracer PET/CT with [18F]FDG in different cancer types, resulting in larger …

S Wegen, J Weindler, CA Voltin, L van Heek… - Strahlentherapie und …, 2024 - Springer
Purpose Fibroblast activation protein (FAP) detected by positron-emission tomography
(PET) using fibroblast activation protein inhibitor (FAPI) appears to be a promising target for …

Diagnostic yield of FAP-guided positron emission tomography in thyroid cancer: a systematic review

A Rizzo, D Albano, F Dondi, M Cioffi, B Muoio… - Frontiers in …, 2024 - frontiersin.org
Background Several recent studies have proposed the possible application of positron
emission tomography/computed tomography (PET/CT) administering radiolabelled fibroblast …