Early life stress and development of the endocannabinoid system: A bidirectional process in programming future coping
S Goldstein Ferber, V Trezza… - Developmental …, 2021 - Wiley Online Library
The endocannabinoid system (ECS) critically regulates stress responsivity and emotional
behavior throughout development. It regulates anxiety‐like behaviors in humans and animal …
behavior throughout development. It regulates anxiety‐like behaviors in humans and animal …
Role of GPR55 during axon growth and target innervation
Guidance molecules regulate the navigation of retinal ganglion cell (RGC) projections
toward targets in the visual thalamus. In this study, we demonstrate that the G-protein …
toward targets in the visual thalamus. In this study, we demonstrate that the G-protein …
Druggable lipid GPCRs: past, present, and prospects
H Mizuno, Y Kihara - Druggable Lipid Signaling Pathways, 2020 - Springer
G protein-coupled receptors (GPCRs) have seven transmembrane spanning domains and
comprise the largest superfamily with~ 800 receptors in humans. GPCRs are attractive …
comprise the largest superfamily with~ 800 receptors in humans. GPCRs are attractive …
Astrocyte-derived phosphatidic acid promotes dendritic branching
YB Zhu, W Gao, Y Zhang, F Jia, HL Zhang, YZ Liu… - Scientific reports, 2016 - nature.com
Astrocytes play critical roles in neural circuit formation and function. Recent studies have
revealed several secreted and contact-mediated signals from astrocytes which are essential …
revealed several secreted and contact-mediated signals from astrocytes which are essential …
Druggable lysophospholipid signaling pathways
K Yanagida, WJ Valentine - Druggable Lipid Signaling Pathways, 2020 - Springer
Lysophosphatidic acid (LPA) has major roles as a bioactive signaling molecule, with
multiple physiological and pathological roles being described in almost every major organ …
multiple physiological and pathological roles being described in almost every major organ …
Expression and Function of the Endocannabinoid System in the Retina and the Visual Brain
JF Bouchard, C Casanova, B Cécyre… - Neural …, 2016 - Wiley Online Library
Endocannabinoids are important retrograde modulators of synaptic transmission throughout
the nervous system. Cannabinoid receptors are seven transmembrane G‐protein coupled …
the nervous system. Cannabinoid receptors are seven transmembrane G‐protein coupled …
Inflammatory and neuropathic nociception is preserved in GPR55 knockout mice
The G-protein coupled receptor GPR55 has been postulated to serve as a novel
cannabinoid receptor. A previous report indicated that GPR55 knockout mice fail to develop …
cannabinoid receptor. A previous report indicated that GPR55 knockout mice fail to develop …
[HTML][HTML] Transcriptome research of human amniocytes identifies hub genes associated with developmental dysplasia in down syndrome
Z Guo, H Xiao, W Yang, T Li, B Hao, S Liao - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Trisomy 21, or Down syndrome (DS), is the most frequent human autosomal chromosome
aneuploidy, which leads to multiple developmental disorders, especially mental retardation …
aneuploidy, which leads to multiple developmental disorders, especially mental retardation …
GPR55-mediated effects on brain microvascular endothelial cells and the blood–brain barrier
LM Leo, B Familusi, M Hoang, R Smith, K Lindenau… - Neuroscience, 2019 - Elsevier
GPR55, an atypical cannabinoid receptor activated by lysophosphatidylinositol (LPI) has
been involved in various physiological and pathological processes. We examined the effect …
been involved in various physiological and pathological processes. We examined the effect …
GPR55 contributes to neutrophil recruitment and mechanical pain induction after spinal cord compression in mice
T Ono, T Yamashita, R Kano, M Inoue, S Okada… - Brain, Behavior, and …, 2023 - Elsevier
Pain transmission and processing in the nervous system are modulated by various
biologically active substances, including lysophospholipids, through direct and indirect …
biologically active substances, including lysophospholipids, through direct and indirect …