[HTML][HTML] The many roles of lysophospholipid mediators and Japanese contributions to this field

Y Takagi, S Nishikado, J Omi, J Aoki - Biological and Pharmaceutical …, 2022 - jstage.jst.go.jp
Lysophospholipids are phospholipids with only one fatty acid. During the past two decades,
it has become apparent that lysophospholipids are not merely degradation products but …

Phosphatidylglucose alleviates atherosclerosis by increasing cholesterol alienation to bile acids and cholesterol efflux in ApoE−/− mice

JY Yang, TT Zhang, ZL Yu, XY Li… - Journal of the …, 2023 - Wiley Online Library
BACKGROUND Phosphatidylcholine (PC) is considered to be the major dietary source for
choline, which is associated with atherosclerosis progress. Thus, phosphatidylglucose (PG) …

Lysophosphatidylinositol induced morphological changes and stress fiber formation through the GPR55-RhoA-ROCK pathway

K Nakajima, S Oka, T Tanikawa… - International Journal of …, 2022 - mdpi.com
We previously reported that lysophosphatidylinositol (LPI) functions as an endogenous
agonist of GPR55, a novel cannabinoid receptor. However, the physiological roles of LPI …

Diverse functions of lipids and lipid metabolism in development

Y Yao, L Ding, X Huang - Small Methods, 2020 - Wiley Online Library
Developmental processes result from interactions between the external environment and
internal factors. Recent discoveries have demonstrated the essential roles of lipid metabolic …

Construction and reconstruction of brain circuits: normal and pathological axon guidance

S Roig-Puiggros, RJ Vigouroux… - Journal of …, 2020 - Wiley Online Library
Perception of our environment entirely depends on the close interaction between the central
and peripheral nervous system. In order to communicate each other, both systems must …

Optic nerve regeneration after crush remodels the injury site: molecular insights from imaging mass spectrometry

DT Stark, DMG Anderson, JMK Kwong… - … & visual science, 2018 - iovs.arvojournals.org
Purpose: Mammalian central nervous system axons fail to regenerate after injury.
Contributing factors include limited intrinsic growth capacity and an inhibitory glial …

Identification of crucial amino acid residues involved in agonist signaling at the GPR55 receptor

MA Lingerfelt, P Zhao, HP Sharir, DP Hurst… - Biochemistry, 2017 - ACS Publications
GPR55 is a newly deorphanized class A G-protein-coupled receptor that has been
implicated in inflammatory pain, neuropathic pain, metabolic disorder, bone development …

[HTML][HTML] Where does axon guidance lead us?

E Stoeckli - F1000Research, 2017 - ncbi.nlm.nih.gov
During neural circuit formation, axons need to navigate to their target cells in a complex,
constantly changing environment. Although we most likely have identified most axon …

The spastic paraplegia-associated phospholipase DDHD1 is a primary brain phosphatidylinositol lipase

JM Inloes, H Jing, BF Cravatt - Biochemistry, 2018 - ACS Publications
Deleterious mutations in the serine hydrolase DDHD domain containing 1 (DDHD1) cause
the SPG28 subtype of the neurological disease hereditary spastic paraplegia (HSP), which …

Tunable protein/cell binding and interaction with neurite outgrowth of low-impedance zwitterionic PEDOTs

YQ Zhang, HA Lin, QC Pan, SH Qian… - … applied materials & …, 2020 - ACS Publications
Zwitterionic poly (3, 4-ethylenedioxythiophene)(PEDOT) is an effective electronic material for
bioelectronics because it exhibits efficient electrical trade-off and diminishes immune …