Scotopic vision in the monkey is modulated by the G protein-coupled receptor 55

J Bouskila, V Harrar, P Javadi, C Casanova… - Visual …, 2016 - cambridge.org
The endogenous cannabinoid system plays important roles in the retina of mice and
monkeys via their classic CB1 and CB2 receptors. We have previously reported that the G …

Separation and analysis of mono-glucosylated lipids in brain and skin by hydrophilic interaction chromatography based on carbohydrate and lipid moiety

K Nakajima, H Akiyama, K Tanaka… - … of Chromatography B, 2016 - Elsevier
Mono-glycosylated sphingolipids and glycerophospholipids play important roles in diverse
biological processes and are linked to a variety of pathologies, such as Parkinson disease …

Preference for glucose over inositol headgroup during lysolipid activation of G protein-coupled receptor 55

AT Guy, K Kano, J Ohyama, H Kamiguchi… - ACS Chemical …, 2018 - ACS Publications
G protein-coupled receptor 55 (GPR55) is highly expressed in brain and peripheral nervous
system. Originally deorphanized as a cannabinoid receptor, recently GPR55 has been …

Specific phospholipids regulate the acquisition of neuronal and astroglial identities in post-mitotic cells

A Montaner, TT da Silva Santana, T Schroeder… - Scientific reports, 2018 - nature.com
Hitherto, the known mechanisms underpinning cell-fate specification act on neural
progenitors, affecting their commitment to generate neuron or glial cells. Here, we show that …

Protecting-group-free glycosylation of phosphatidic acid in aqueous media

K Kano, N Ishii, A Miyagawa, H Takeda… - Organic & …, 2023 - pubs.rsc.org
The glycosylation of unprotected carbohydrates has emerged as an area of significant
interest because it obviates the need for long reaction sequences involving protecting-group …

Direct enzymatic synthesis of 1‐phosphatidyl‐β‐d‐glucose by engineered phospholipase D

A Inoue, M Adachi, J Damnjanović, H Nakano… - …, 2016 - Wiley Online Library
A simple, direct method for the synthesis of 1‐phosphatidyl‐β‐D‐glucose (1‐PGlc) was
established, being the first example of direct enzymatic synthesis of this recently discovered …

Integrated lipidomic and transcriptomic analysis reveals clarithromycin-induced alteration of glycerophospholipid metabolism in the cerebral cortex of mice

X Wang, L Wang, M Luo, Q Bu, C Liu, L Jiang… - Cell Biology and …, 2023 - Springer
Clarithromycin (CLA) has been widely used in the treatment of bacterial infection. Research
reveals the adverse effects on the central nervous system among patients receiving CLA …

Stereocontrolled Synthesis of Lyso‐phosphatidyl β‐D‐Glucoside

K Kano, N Ishii, Y Hirabayashi, H Kamiguchi… - …, 2021 - Wiley Online Library
Lyso‐phosphatidyl β‐D‐glucoside (lysoPtdGlc) is during embryonic development a neurite
growth cone guidance cue associated with G‐protein coupled receptor 55, and has been …

Development of chromen-4-one derivatives as (Ant) agonists for the lipid-activated G Protein-Coupled Receptor GPR55 with Tunable Efficacy

CT Schoeder, A Meyer, AB Mahardhika, D Thimm… - ACS …, 2019 - ACS Publications
The lipid-activated G protein-coupled receptor (GPCR) GPR55 has been proposed as a
drug target for the treatment of chronic diseases including inflammation, neurodegeneration …

[HTML][HTML] Lipid droplets in the nervous system: involvement in cell metabolic homeostasis

Y Zhang, Y Chen, C Zhuang, J Qi… - Neural Regeneration …, 2025 - journals.lww.com
Lipid droplets serve as primary storage organelles for neutral lipids in neurons, glial cells,
and other cells in the nervous system. Lipid droplet formation begins with the synthesis of …