[HTML][HTML] Exercise is medicine for nonalcoholic fatty liver disease: exploration of putative mechanisms
Exercise remains a key component of nonalcoholic fatty liver disease (NAFLD) treatment.
The mechanisms that underpin improvements in NAFLD remain the focus of much …
The mechanisms that underpin improvements in NAFLD remain the focus of much …
[HTML][HTML] Autophagy: A Cellular Guardian against Hepatic Lipotoxicity
RA Sinha - Genes, 2023 - mdpi.com
Lipotoxicity is a phenomenon of lipid-induced cellular injury in nonadipose tissue. Excess of
free saturated fatty acids (SFAs) contributes to hepatic injury in nonalcoholic fatty liver …
free saturated fatty acids (SFAs) contributes to hepatic injury in nonalcoholic fatty liver …
Thyroid function, adipokines and mitokines in metabolic dysfunction‐associated steatohepatitis: A multi‐centre biopsy‐based observational study
M Kouvari, L Valenzuela‐Vallejo… - Liver …, 2024 - Wiley Online Library
Abstract Background and Aims Thyroid axis is currently under investigation as a therapeutic
target in metabolic dysfunction‐associated steatotic liver disease (MASLD). Thyroid function …
target in metabolic dysfunction‐associated steatotic liver disease (MASLD). Thyroid function …
Emerging drug therapies for metabolic dysfunction-associated steatotic liver disease: a glimpse into the horizon
Abstract Purpose of Review Metabolic dysfunction–associated steatotic liver disease
(MASLD) and its aggressive form, metabolic dysfunction-associated steatohepatitis (MASH) …
(MASLD) and its aggressive form, metabolic dysfunction-associated steatohepatitis (MASH) …
Hormone action and liver disease, a complex interplay
Thyroid hormone action is involved in virtually all physiological processes. It is well known
that the liver and thyroid are intimately linked, with thyroid hormone playing important roles …
that the liver and thyroid are intimately linked, with thyroid hormone playing important roles …
Inflammatory liver diseases and susceptibility to sepsis
H Lu - Clinical Science, 2024 - portlandpress.com
Patients with inflammatory liver diseases, particularly alcohol-associated liver disease and
metabolic dysfunction-associated fatty liver disease (MAFLD), have higher incidence of …
metabolic dysfunction-associated fatty liver disease (MAFLD), have higher incidence of …
siRNA-mediated gene silencing for non-alcoholic fatty liver disease: A comprehensive review of molecular targets
A Mahmoudi, M Rostami, MM Hajihasani… - European Polymer …, 2024 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a burgeoning global public health distress, with
an estimated 25% of the world population affected. Despite the increasing prevalence and …
an estimated 25% of the world population affected. Despite the increasing prevalence and …
TRβ Agonism Induces Tumor Suppression and Enhances Drug Efficacy in Anaplastic Thyroid Cancer in Female Mice
NE Gillis, LM Cozzens, ER Wilson, NM Smith… - …, 2023 - academic.oup.com
Thyroid hormone receptor beta (TRβ) is a recognized tumor suppressor in numerous solid
cancers. The molecular signaling of TRβ has been elucidated in several cancer types …
cancers. The molecular signaling of TRβ has been elucidated in several cancer types …
[HTML][HTML] Targeting nuclear receptors for NASH/MASH: From bench to bedside
RA Sinha - Liver research, 2024 - Elsevier
The onset of metabolic dysfunction-associated steatohepatitis (MASH) or non-alcoholic
steatohepatitis (NASH) represents a tipping point leading to liver injury and subsequent …
steatohepatitis (NASH) represents a tipping point leading to liver injury and subsequent …
A thyroid hormone receptor beta specific agonist suppresses anaplastic thyroid cancer cell phenotype and increases efficacy of therapeutic agents
Background Anaplastic thyroid cancer (ATC) is one of the most lethal endocrine cancers,
with an average survival time of six months after diagnosis. These aggressive tumors have …
with an average survival time of six months after diagnosis. These aggressive tumors have …