Over the last five decades, a large body of evidence has accrued for structural and metabolic
brain alterations in schizophrenia. Here we provide an overview of these findings, focusing …

Schizophrenia was initially defined as “dementia praecox” by E. Kraepelin, which implies
progressive deterioration. However, recent studies have revealed that early effective …

In the brain, astrocytes regulate shape and functions of the synaptic and vascular
compartments through a variety of released factors and membrane-bound proteins. An …

Background Elevated maternal psychological distress during pregnancy is linked to adverse
outcomes in offspring. The potential effects of intensified levels of maternal distress during …

Abstract Language impairment is comorbid in most children with Autism Spectrum Disorder
(ASD) but its neural basis is poorly understood. Using structural magnetic resonance …

Growing evidence supports that prenatal processes play an important role for cognitive
ability in normal and clinical conditions. In this context, several neuroimaging studies …

Genetic associations with macroscopic brain structure can provide insights into brain
function and disease. However, specific associations with measures of local brain folding …

Previous magnetic resonance imaging (MRI) studies reported increased brain gyrification in
schizophrenia and schizotypal disorder, a prototypic disorder within the schizophrenia …

Background: The majority of models on obsessive compulsive disorder (OCD) endorse a top-
down perspective on the cognitive mechanisms underlying OCD functioning and …

Deficit syndrome schizophrenia is a characteristic subtype defined by persistent negative
symptoms and poor functional outcomes; however, the biological mechanisms underlying …