[HTML][HTML] Synaptic plasticity and mental health: methods, challenges and opportunities

LG Appelbaum, MA Shenasa, L Stolz… - …, 2023 - nature.com
Activity-dependent synaptic plasticity is a ubiquitous property of the nervous system that
allows neurons to communicate and change their connections as a function of past …

Oxidative stress‐related mechanisms in schizophrenia pathogenesis and new treatment perspectives

EA Ermakov, EM Dmitrieva… - Oxidative Medicine …, 2021 - Wiley Online Library
Schizophrenia is recognized to be a highly heterogeneous disease at various levels, from
genetics to clinical manifestations and treatment sensitivity. This heterogeneity is also …

Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain

RA Hill, AM Li, J Grutzendler - Nature neuroscience, 2018 - nature.com
Axonal myelin increases neural processing speed and efficiency. It is unknown whether
patterns of myelin distribution are fixed or whether myelinating oligodendrocytes are …

Oligodendrocyte death initiates synchronous remyelination to restore cortical myelin patterns in mice

TW Chapman, GE Olveda, X Bame, E Pereira… - Nature …, 2023 - nature.com
Myelin degeneration occurs in neurodegenerative diseases and aging. In these conditions,
resident oligodendrocyte progenitor cells (OPCs) differentiate into oligodendrocytes that …

[HTML][HTML] Dynamics and mechanisms of CNS myelination

KK Bercury, WB Macklin - Developmental cell, 2015 - cell.com
Vertebrate myelination is an evolutionary advancement essential for motor, sensory, and
higher-order cognitive function. CNS myelin, a multilamellar differentiation of the …

Age-related microstructural differences quantified using myelin water imaging and advanced diffusion MRI

T Billiet, M Vandenbulcke, B Mädler, R Peeters… - Neurobiology of …, 2015 - Elsevier
Age-related microstructural differences have been detected using diffusion tensor imaging
(DTI). Although DTI is sensitive to the effects of aging, it is not specific to any underlying …

Prenatal stress and the developing brain: Risks for neurodevelopmental disorders

BRH Van den Bergh, R Dahnke… - Development and …, 2018 - cambridge.org
The prenatal period is increasingly considered as a crucial target for the primary prevention
of neurodevelopmental and psychiatric disorders. Understanding their pathophysiological …

Deep cervical lymph node ligation aggravates AD‐like pathology of APP/PS1 mice

L Wang, Y Zhang, Y Zhao, C Marshall, T Wu… - Brain …, 2019 - Wiley Online Library
The imbalance between production and clearance of amyloid‐beta (Aβ) is a key step in the
onset and development of Alzheimer's disease (AD). Therefore, reducing Aβ accumulation …

Advances in noninvasive myelin imaging

F Heath, SA Hurley, H Johansen‐Berg… - Developmental …, 2018 - Wiley Online Library
Myelin is important for the normal development and healthy function of the nervous system.
Recent developments in MRI acquisition and tissue modeling aim to provide a better …

[HTML][HTML] Insights into myelin dysfunction in schizophrenia and bipolar disorder

M Valdés-Tovar, AM Rodríguez-Ramírez… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Schizophrenia and bipolar disorder are disabling psychiatric disorders with a worldwide
prevalence of approximately 1%. Both disorders present chronic and deteriorating …