[HTML][HTML] The lactate and the lactate dehydrogenase in inflammatory diseases and major risk factors in COVID-19 patients

GS Gupta - Inflammation, 2022 - Springer
Lactate dehydrogenase (LDH) is a terminating enzyme in the metabolic pathway of
anaerobic glycolysis with end product of lactate from glucose. The lactate formation is crucial …

[HTML][HTML] Diet-derived antioxidants: the special case of ergothioneine

B Halliwell, RMY Tang, IK Cheah - Annual Review of Food …, 2023 - annualreviews.org
This article reviews what is presently known about the biological roles of the diet-derived
compound ergothioneine (ET). ET seems important to humans because it is rapidly taken up …

[HTML][HTML] Plasma proteomics identify biomarkers and pathogenesis of COVID-19

T Shu, W Ning, D Wu, J Xu, Q Han, M Huang, X Zou… - Immunity, 2020 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic is a global public health
crisis. However, little is known about the pathogenesis and biomarkers of COVID-19. Here …

[HTML][HTML] Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may …

A Kruger, M Vlok, S Turner, C Venter… - Cardiovascular …, 2022 - Springer
Background Post-acute sequelae of COVID-19 (PASC), also now known as long COVID,
has become a major global health and economic burden. Previously, we provided evidence …

[HTML][HTML] Large-scale plasma analysis revealed new mechanisms and molecules associated with the host response to SARS-CoV-2

E Barberis, S Timo, E Amede, VV Vanella… - International journal of …, 2020 - mdpi.com
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to
nearly every continent, registering over 1,250,000 deaths worldwide. The effects of SARS …

Integrative modeling of quantitative plasma lipoprotein, metabolic, and amino acid data reveals a multiorgan pathological signature of SARS-CoV-2 infection

T Kimhofer, S Lodge, L Whiley, N Gray… - Journal of proteome …, 2020 - ACS Publications
The metabolic effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection on human blood plasma were characterized using multiplatform metabolic …

[HTML][HTML] Proteomic and metabolomic profiling of urine uncovers immune responses in patients with COVID-19

X Bi, W Liu, X Ding, S Liang, Y Zheng, X Zhu, S Quan… - Cell reports, 2022 - cell.com
The utility of the urinary proteome in infectious diseases remains unclear. Here, we analyzed
the proteome and metabolome of urine and serum samples from patients with COVID-19 …

[HTML][HTML] Cutting edge: severe SARS-CoV-2 infection in humans is defined by a shift in the serum lipidome, resulting in dysregulation of eicosanoid immune mediators

B Schwarz, L Sharma, L Roberts, X Peng… - The Journal of …, 2021 - journals.aai.org
The COVID-19 pandemic has affected more than 20 million people worldwide, with mortality
exceeding 800,000 patients. Risk factors associated with severe disease and mortality …

[HTML][HTML] SARS-CoV-2 infection dysregulates the metabolomic and lipidomic profiles of serum

C Bruzzone, M Bizkarguenaga, R Gil-Redondo… - Iscience, 2020 - cell.com
COVID-19 is a systemic infection that exerts significant impact on the metabolism. Yet, there
is little information on how SARS-CoV-2 affects metabolism. Using NMR spectroscopy, we …

[HTML][HTML] Metabolomics study of COVID-19 patients in four different clinical stages

A Valdés, LO Moreno, SR Rello, A Orduña… - Scientific reports, 2022 - nature.com
Abstract SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is the coronavirus
strain causing the respiratory pandemic COVID-19 (coronavirus disease 2019). To …