During hemolysis, erythrophagocytes dispose damaged red blood cells. This prevents the
extracellular release of hemoglobin, detoxifies heme, and recycles iron in a linked metabolic …

Over the last two decades, neurological researchers have uncovered many
pathophysiological mechanisms associated with subarachnoid haemorrhage (SAH), with …

In at least some individuals who suffer a traumatic brain injury (TBI), there exists a risk of
future neurodegenerative illness. This review focuses on the association between the brain …

Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating form of stroke frequently
affecting young to middle-aged adults, with an unmet need to improve outcome. This special …

Delayed cerebral ischemia (DCI) continues to be a sequela of aneurysmal subarachnoid
hemorrhage (aSAH) that carries significant morbidity and mortality. Aside from nimodipine …

After intracranial hemorrhage, heme is released from cell-free hemoglobin. This red blood
cell component may drive secondary brain injury at the hematoma‒brain interface. This …

Background Delayed cerebral ischemia (DCI) continues to be a significant contributor to
morbidity and mortality following aneurysmal subarachnoid hemorrhage (aSAH) …

Subarachnoid hemorrhage (SAH) is a type of hemorrhagic stroke resulting from the rupture
of an arterial vessel within the brain. Unlike other stroke types, SAH affects both young …

The dramatic increase in intracranial pressure after subarachnoid hemorrhage leads to a
decrease in cerebral perfusion pressure and a reduction in cerebral blood flow …

Objectives Cerebrospinal fluid hemoglobin has been positioned as a potential biomarker
and drug target for aneurysmal subarachnoid hemorrhage-related secondary brain injury …