Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products

M Ibrahim, E Ramadan, NE Elsadek, SE Emam… - Journal of Controlled …, 2022 - Elsevier
Polyethylene glycol (PEG) is a versatile polymer that is widely used as an additive in foods
and cosmetics, and as a carrier in PEGylated therapeutics. Even though PEG is thought to …

[HTML][HTML] Adenoviral vector vaccine platforms in the SARS-CoV-2 pandemic

SA Mendonça, R Lorincz, P Boucher, DT Curiel - npj Vaccines, 2021 - nature.com
Adenoviral vectors have been explored as vaccine agents for a range of infectious diseases,
and their ability to induce a potent and balanced immune response made them logical …

Anti-PEG antibodies boosted in humans by SARS-CoV-2 lipid nanoparticle mRNA vaccine

Y Ju, WS Lee, EH Pilkington, HG Kelly, S Li, KJ Selva… - Acs Nano, 2022 - ACS Publications
Humans commonly have low level antibodies to poly (ethylene) glycol (PEG) due to
environmental exposure. Lipid nanoparticle (LNP) mRNA vaccines for SARS-CoV-2 contain …

[HTML][HTML] An updated review of SARS-CoV-2 vaccines and the importance of effective vaccination programs in pandemic times

C García-Montero, O Fraile-Martínez, C Bravo… - Vaccines, 2021 - mdpi.com
Since the worldwide COVID-19 pandemic was declared a year ago, the search for vaccines
has become the top priority in order to restore normalcy after 2.5 million deaths worldwide …

[HTML][HTML] Allergic reactions to current available COVID-19 vaccinations: pathophysiology, causality, and therapeutic considerations

NG Kounis, I Koniari, C de Gregorio, D Velissaris… - Vaccines, 2021 - mdpi.com
Vaccines constitute the most effective medications in public health as they control and
prevent the spread of infectious diseases and reduce mortality. Similar to other medications …

A systematic review on mucocutaneous presentations after COVID‐19 vaccination and expert recommendations about vaccination of important immune‐mediated …

F Seirafianpour, H Pourriyahi… - Dermatologic …, 2022 - Wiley Online Library
With dermatologic side effects being fairly prevalent following vaccination against COVID‐
19, and the multitude of studies aiming to report and analyze these adverse events, the need …

[HTML][HTML] COVID-19 vaccination of patients with allergies and type-2 inflammation with concurrent antibody therapy (biologicals)–A Position Paper of the German …

O Pfaar, L Klimek, E Hamelmann… - Allergologie …, 2021 - ncbi.nlm.nih.gov
Background: After the beginning and during the worldwide pandemic caused by the severe
acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), patients with allergic and …

Normalization of Tumor Vessels by Lenvatinib‐Based Metallo‐Nanodrugs Alleviates Hypoxia and Enhances Calreticulin‐Mediated Immune Responses in Orthotopic …

D Zhang, C Jiang, X Zheng, Z Lin, Q Zhuang, H Xie… - Small, 2023 - Wiley Online Library
Immunocheckpoint inhibitors combined with Lenvatinib is the first line treatment for
hepatocellular carcinoma (HCC), but their potency is hampered by the low response rate …

[HTML][HTML] Adverse effects of COVID-19 vaccination: machine learning and statistical approach to identify and classify incidences of morbidity and postvaccination …

MM Ahamad, S Aktar, MJ Uddin, M Rashed-Al-Mahfuz… - Healthcare, 2022 - mdpi.com
Good vaccine safety and reliability are essential for successfully countering infectious
disease spread. A small but significant number of adverse reactions to COVID-19 vaccines …

[HTML][HTML] Brief on recent application of liposomal vaccines for lower respiratory tract viral infections: From influenza to COVID-19 vaccines

MA Attia, EA Essa, TT Elebyary, AM Faheem… - Pharmaceuticals, 2021 - mdpi.com
Vaccination is the most effective means of preventing infectious diseases and saving lives.
Modern biotechnology largely enabled vaccine development. In the meantime, recent …