[PDF][PDF] Models of the cerebellum and motor learning

JC Houk, JT Buckingham, AG Barto - Behavioral and brain sciences, 1996 - academia.edu
This article reviews models of the cerebellum and motor learning starting with the landmark
papers by Marr and Albus and going through present times. The unique architecture of the …

AMPA receptor trafficking and learning

J Keifer, Z Zheng - European Journal of Neuroscience, 2010 - Wiley Online Library
In the last few years it has become clear that AMPA‐type glutamate neurotransmitter
receptors are rapidly transported into and out of synapses to strengthen or weaken their …

Oligomeric amyloid-β inhibits the proteolytic conversion of brain-derived neurotrophic factor (BDNF), AMPA receptor trafficking, and classical conditioning

Z Zheng, B Sabirzhanov, J Keifer - Journal of Biological Chemistry, 2010 - ASBMB
Amyloid-β (Aβ) peptide is thought to have a significant role in the progressive memory loss
observed in patients with Alzheimer disease and inhibits synaptic plasticity in animal models …

Comparative Genomics of the BDNF Gene, Non-Canonical Modes of Transcriptional Regulation, and Neurological Disease

J Keifer - Molecular Neurobiology, 2021 - Springer
Alternative splicing of genes in the central nervous system is ubiquitous and utilizes many
different mechanisms. Splicing generates unique transcript or protein isoforms of the primary …

Diffuse distribution of sulforhodamine‐labeled neurons during serotonin‐evoked locomotion in the neonatal rat thoracolumbar spinal cord

C Cina, S Hochman - Journal of Comparative Neurology, 2000 - Wiley Online Library
The fluorescent dye sulforhodamine‐101 undergoes synaptic activity‐dependent
endocytotic uptake and consequent retrograde transport in presynaptic neurons. We used …

BDNF-induced synaptic delivery of AMPAR subunits is differentially dependent on NMDA receptors and requires ERK

W Li, J Keifer - Neurobiology of learning and memory, 2009 - Elsevier
Previous studies using an in vitro model of eyeblink classical conditioning in turtles suggest
that increased numbers of synaptic AMPARs supports the acquisition and expression of …

Cleavage of proBDNF to BDNF by a tolloid-like metalloproteinase is required for acquisition of in vitro eyeblink classical conditioning

J Keifer, BE Sabirzhanov, Z Zheng, W Li… - Journal of …, 2009 - Soc Neuroscience
The tolloid/bone morphogenetic protein-1 family of metalloproteinases have an important
role in the regulation of embryonic pattern formation and tissue morphogenesis. Studies …

Discharge profiles of abducens, accessory abducens, and orbicularis oculi motoneurons during reflex and conditioned blinks in alert cats

JA Trigo, A Gruart… - Journal of …, 1999 - journals.physiology.org
Discharge profiles of abducens, accessory abducens, and orbicularis oculi motoneurons
during reflex and conditioned blinks in alert cats. The discharge profiles of identified …

Coordinate action of pre-and postsynaptic brain-derived neurotrophic factor is required for AMPAR trafficking and acquisition of in vitro classical conditioning

W Li, J Keifer - Neuroscience, 2008 - Elsevier
Brain-derived neurotrophic factor (BDNF) has been implicated in mechanisms of synaptic
plasticity such as long-term potentiation (LTP), but its role in associative learning remains …

Expression of the immediate-early gene–encoded protein Egr-1 (zif268) during in vitro classical conditioning

M Mokin, J Keifer - Learning & Memory, 2005 - learnmem.cshlp.org
Expression of the immediate-early genes (IEGs) has been shown to be induced by activity-
dependent synaptic plasticity or behavioral training and is thought to play an important role …