[HTML][HTML] Cryo-electron microscopy of IgM-VAR2CSA complex reveals IgM inhibits binding of Plasmodium falciparum to Chondroitin Sulfate A
RR Akhouri, S Goel, U Skoglund - Nature Communications, 2023 - nature.com
Placental malaria is caused by Plasmodium falciparum-infected erythrocytes (IEs) adhering
to chondroitin sulfate proteoglycans in placenta via VAR2CSA-type PfEMP1. Human …
to chondroitin sulfate proteoglycans in placenta via VAR2CSA-type PfEMP1. Human …
Immunoglobulin M perception by FcμR
Y Li, H Shen, R Zhang, C Ji, Y Wang, C Su, J Xiao - Nature, 2023 - nature.com
Immunoglobulin M (IgM) is the first antibody to emerge during embryonic development and
the humoral immune response. IgM can exist in several distinct forms, including monomeric …
the humoral immune response. IgM can exist in several distinct forms, including monomeric …
CD5L associates with IgM via the J chain
Y Wang, C Su, C Ji, J Xiao - bioRxiv, 2023 - biorxiv.org
CD5 antigen-like (CD5L), also known as Spa; or AIM (Apoptosis inhibitor of macrophage),
emerges as an integral component of serum immunoglobulin M (IgM). However, the …
emerges as an integral component of serum immunoglobulin M (IgM). However, the …
Targeting Apicoplasts in Plasmodium falciparum, Origin and Pathways
The apicoplast is an important source of antimalarial drug target. The in-depth evaluation
and examination showed that apicoplast is a potent pharmacological target that is …
and examination showed that apicoplast is a potent pharmacological target that is …
Proteome-wide comparison of tertiary protein structures reveal extensive molecular mimicry in Plasmodium-human interactions
V Muthye, JD Wasmuth - bioRxiv, 2023 - biorxiv.org
Molecular mimicry is a strategy used by parasites to escape the host immune system and
successfully transmit to a new host. To date, high-throughput examples of molecular mimicry …
successfully transmit to a new host. To date, high-throughput examples of molecular mimicry …
CD5L associates with IgM via the J chain
J Xiao, Y Wang, C Su, C Ji - 2024 - researchsquare.com
Abstract CD5 antigen-like (CD5L), also known as Spα or AIM (Apoptosis inhibitor of
macrophage), emerges as an integral component of serum immunoglobulin M (IgM) …
macrophage), emerges as an integral component of serum immunoglobulin M (IgM) …