Special considerations in the design and implementation of pediatric otoprotection trials

DR Freyer, E Orgel, K Knight, M Krailo - Journal of Cancer Survivorship, 2023 - Springer
Purpose Cisplatin-induced hearing loss (CIHL) is a common late effect after childhood
cancer treatment having profound, lifelong consequences that lower quality of life. The …

The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a …

OR Phillips, DM Baguley, SE Pearson… - Journal of Cancer …, 2023 - Springer
Purpose To elucidate the long-term impacts of hearing loss, tinnitus and balance in people
living with and beyond cancer (LWBC) treated with platinum-based chemotherapy (PBCT) …

Neurocognitive and behavioral outcomes of Chinese survivors of childhood lymphoblastic leukemia

L Peng, LS Yang, P Yam, CS Lam, AS Chan… - Frontiers in …, 2021 - frontiersin.org
Background Increasing attention has been dedicated to investigate modifiable risk factors of
late effects in survivors of childhood cancer. This study aims to evaluate neurocognitive and …

Modeling the risk of hearing loss from radiation therapy in childhood cancer survivors: A PENTEC comprehensive review

B Murphy, A Jackson, JK Bass, DS Tsang… - International Journal of …, 2024 - Elsevier
Purpose The Pediatric Normal Tissue Effects in the Clinic (PENTEC) hearing loss (HL) task
force reviewed investigations on cochlear radiation dose-response relationships and risk …

[HTML][HTML] Neurotoxic effects of childhood cancer therapy and its potential neurocognitive impact

NS Phillips, ES Duke, HLT Schofield… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
A new era of treatment for childhood cancer has welcomed an increasing number of long-
term survivors, for whom acute and late neurologic and neurocognitive sequelae related to …

Sodium thiosulfate as cisplatin otoprotectant in children: the challenge of when to use it

P Brock, A Meijer, P Kogner, M Ansari… - Pediatric blood & …, 2023 - pubmed.ncbi.nlm.nih.gov
Sodium thiosulfate as cisplatin otoprotectant in children: The challenge of when to use it
Sodium thiosulfate as cisplatin otoprotectant in children: The challenge of when to use it Pediatr …

Patient-reported neurocognitive function in adult survivors of childhood and adolescent osteosarcoma and Ewing sarcoma

NS Kadan-Lottick, DJ Zheng, M Wang… - Journal of Cancer …, 2023 - Springer
Purpose Little is known regarding long-term neurocognitive outcomes in osteosarcoma and
Ewing sarcoma (EWS) survivors despite potential risk factors. We evaluated associations …

Hearing loss after radiation and chemotherapy for CNS and head-and-neck tumors in children

D Keilty, M Khandwala, ZA Liu… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Hearing loss (HL) is a serious secondary effect of treatment for CNS and head-
and-neck tumors in children. The goal of this study was to evaluate incidence and risk …

High-dose chemotherapy in children with newly diagnosed medulloblastoma

L Lafay-Cousin, C Dufour - Cancers, 2022 - mdpi.com
Simple Summary Medulloblastoma is the most common malignant central nervous system
tumor in the pediatric population. Treatment modalities are stratified by age, extent of …

Severity of hearing loss after platinum chemotherapy in childhood cancer survivors

S Strebel, L Mader, T Sláma, N Waespe… - Pediatric blood & …, 2022 - Wiley Online Library
Background Hearing loss is a potential side effect from childhood cancer treatment. We
described the severity of hearing loss assessed by audiometry in a representative national …