Lysosome is the organelle responsible for breaking down macromolecules to maintain
homeostasis and to fight infection. The disruption of normal lysosomal function due to …

Mucopolysaccharidoses (MPS) are genetic metabolic diseases characterized by defects in
the activity of lysosomal hydrolases. In MPS, secondary cell disturbance affects pathways …

Metachromatic leukodystrophy is a neurological lysosomal deposit disease that affects
public health despite its low incidence in the population. Currently, few reports are available …

Physical activity has a positive effect on human health and emotional well-being. However,
in both amateur and professional athletes, training poses a risk of acute or chronic injury …

Abstract Mucolipidosis II and III (MLII and MLIII) are autosomal recessive diseases caused
by pathogenic variants in GNPTAB and GNPTG genes that lead to defects in GlcNAc-1 …

Rebusan bunga pukul empat (Mirabilis jalapa L.) telah digunakan sebagai antiradang
secara tradisional. Skrining fitokimia bunga Mirabilis jalapa L. menunjukkan kandungan …

In Parkinson's disease (PD), several genes have been identified as the PD-related genes,
however, the regulatory mechanisms of these gene expressions have not been fully …

This expert-opinion-based document was prepared by a group of specialists in pediatric
inherited metabolic diseases and infectious diseases including administrative board …

Lysosomal storage disorders are a group of genetic metabolic disorders caused by
dysfunctional endosomal-lysosomal hydrolases, altered vesicular trafficking or biogenesis of …

Heart failure (HF) remains the leading cause of death globally. The progression of HF is
characterized by cardiac mitochondrial dysfunction and aberrant inflammatory responses …