Ferritinophagy: research advance and clinical significance in cancers

J Wang, N Wu, M Peng, L Oyang, X Jiang, Q Peng… - Cell Death …, 2023 - nature.com
Ferritinophagy, a process involving selective autophagy of ferritin facilitated by nuclear
receptor coactivator 4 (NCOA4), entails the recognition of ferritin by NCOA4 and subsequent …

[HTML][HTML] Emerging role of ferroptosis in diabetic kidney disease: molecular mechanisms and therapeutic opportunities

H Wang, D Liu, B Zheng, Y Yang, Y Qiao… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Diabetic kidney disease (DKD) is one of the most common and severe microvascular
complications of diabetes mellitus (DM), and has become the leading cause of end-stage …

Effects of manganese and iron, alone or in combination, on apoptosis in BV2 cells

Y Fang, C Gan, J Peng, Y Xie, H Song, Y Mo… - … Trace Element Research, 2024 - Springer
The aim of study was to address the effects of manganese and iron, alone and in
combination, on apoptosis of BV2 microglia cells, and to determine if combined exposure to …

Human umbilical cord mesenchymal stem cell‐derived exosome suppresses programmed cell death in traumatic brain injury via PINK1/Parkin‐mediated mitophagy

L Zhang, Y Lin, W Bai, L Sun… - CNS Neuroscience & …, 2023 - Wiley Online Library
Aims Recently, human umbilical cord mesenchymal stem cell (HucMSC)‐derived exosome
is a new focus of research in neurological diseases. The present study was aimed to …

Microgravity triggers ferroptosis and accelerates senescence in the MG-63 cell model of osteoblastic cells

N Garbacki, J Willems, T Neutelings, C Lambert… - npj …, 2023 - nature.com
In space, cells sustain strong modifications of their mechanical environment.
Mechanosensitive molecules at the cell membrane regulate mechanotransduction pathways …

Deeper insight into ferroptosis: association with Alzheimer's, Parkinson's disease, and brain tumors and their possible treatment by nanomaterials induced ferroptosis

VK Yadav, N Choudhary, A Gacem, RK Verma… - Redox …, 2023 - Taylor & Francis
Ferroptosis is an emerging and novel type of iron-dependent programmed cell death which
is mainly caused by the excessive deposition of free intracellular iron in the brain cells. This …

Ferroptosis and cuproptosis: Metal-dependent cell death pathways activated in response to classical chemotherapy–Significance for cancer treatment?

M Kciuk, A Gielecińska, Ż Kałuzińska-Kołat… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Apoptosis has traditionally been regarded as the desired cell death pathway activated by
chemotherapeutic drugs due to its controlled and non-inflammatory nature. However, recent …

Emerging roles of ferroptosis in pulmonary fibrosis: current perspectives, opportunities and challenges

Y Hu, Y Huang, L Zong, J Lin, X Liu, S Ning - Cell Death Discovery, 2024 - nature.com
Pulmonary fibrosis (PF) is a chronic interstitial lung disorder characterized by abnormal
myofibroblast activation, accumulation of extracellular matrix (ECM), and thickening of …

[HTML][HTML] O-GlcNAcylation regulates the stability of transferrin receptor (TFRC) to control the ferroptosis in hepatocellular carcinoma cells

X Zhou, Y Wang, X Li, J Zhou, W Yang, X Wang, S Jiao… - Redox Biology, 2024 - Elsevier
Ferroptosis is an iron-dependent programmed cell death (PCD) enforced by lipid
peroxidation accumulation. Transferrin receptor (TFRC), one of the signature proteins of …

Unveiling the intersection: ferroptosis in influenza virus infection

A Letafati, Z Taghiabadi, OS Ardekani, S Abbasi… - Virology Journal, 2024 - Springer
The influenza virus (IFV) imposes a considerable health and economic burden globally,
requiring a comprehensive understanding of its pathogenic mechanisms. Ferroptosis, an …