2021 guideline for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline from the American Heart Association/American Stroke …

DO Kleindorfer, A Towfighi, S Chaturvedi, KM Cockroft… - Stroke, 2021 - Am Heart Assoc
Dawn O. Kleindorfer, MD, FAHA, Chair; Amytis Towfighi, MD, FAHA, Vice Chair; Seemant
Chaturvedi, MD, FAHA; Kevin M. Cockroft, MD, MSc, FAHA; Jose Gutierrez, MD, MPH; …

[HTML][HTML] Benefits and risks of dual versus single antiplatelet therapy for secondary stroke prevention: a systematic review for the 2021 guideline for the prevention of …

DL Brown, DA Levine, K Albright, MK Kapral, LY Leung… - Stroke, 2021 - journals.lww.com
Background: Dual antiplatelet therapy (DAPT) after ischemic stroke or transient ischemic
attack may reduce recurrent stroke but also increase severe bleeding compared with single …

Contemporary antiplatelet therapy for secondary stroke prevention: a narrative review of current literature and guidelines

J Shah, S Liu, W Yu - Stroke and vascular neurology, 2022 - svn.bmj.com
Antiplatelet therapy is one of the mainstays for secondary stroke prevention. This narrative
review aimed to highlight the current evidence and recommendations of antiplatelet therapy …

[HTML][HTML] Efficacy and safety of clopidogrel and/or aspirin for ischemic stroke/transient ischemic attack: An overview of systematic reviews and meta-analysis

Y Yang, Z Huang, X Zhang - Medicine, 2021 - journals.lww.com
Objective: Patients experiencing acute ischemic stroke or transient ischemic attack are
commonly treated with clopidogrel and/or aspirin (mono-and dual-antiplatelet therapy) to …

Human Serum Albumin-enriched Clopidogrel Bisulfate Nanoparticle Alleviates Cerebral Ischemia–Reperfusion Injury in Rats

Y Luo, Y Xia, H Zhang, Y Lin, L He, T Gong… - Pharmaceutical …, 2023 - Springer
Purpose Cerebral ischemia–reperfusion (I/R) injury remains a leading cause of mobility and
mortality among patients with ischemic stroke. This study aims to develop a human serum …

The need of a multicomponent guiding approach to personalize clopidogrel treatment

C Valeria, S Carmine, M Valentina, I Teresa… - The …, 2021 - nature.com
Patients bearing polymorphisms termed CYP2C19 loss of function (LoF) alleles and ABCB1-
C3435T may do not properly respond to standard dosage of clopidogrel and have an …

[HTML][HTML] Recent advances in the management of transient ischemic attacks

J Ortiz-Garcia, CR Gomez, MJ Schneck, J Biller - Faculty Reviews, 2022 - ncbi.nlm.nih.gov
Transient ischemic attack (TIA) constitutes an important clinical condition, indicating the
presence of considerable risk for a subsequent ischemic stroke. Its prompt diagnosis and …

Nonsteroidal anti-inflammatory drugs

V Piskovatska, V Buheruk, O Strilbytska… - Anti-Aging …, 2023 - Elsevier
Aspirin and nonaspirin nonsteroidal anti-inflammatory drugs (naNSAIDs) are prescribed for
pain and fever relief. Evidence from clinical trials shows numerous pleiotropic effects that …

Analysis of CYP2C19 genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study

LC Pilling, D Türkmen, H Fullalove, JL Atkins… - BMJ open, 2021 - bmjopen.bmj.com
Objective To determine whether CYP2C19 loss-of-function (LoF) alleles increase risk of
ischaemic stroke and myocardial infarction (MI) in UK primary care patients prescribed …

Pharmacology and potential role of selatogrel, a subcutaneous platelet P2Y12 receptor antagonist

WAE Parker, RF Storey - Expert Opinion on Emerging Drugs, 2020 - Taylor & Francis
Atherothrombosis of the coronary, cerebral, or peripheral arteries may lead to acute
coronary syndromes (ACS), stroke/transient ischemic attack (TIA) and acute limb ischemia …