Orodispersible Films (ODFs) are drug delivery systems manufactured with a wide range of
methods on a big scale or for customized medicines and small-scale pharmacy. Both ODFs …

Introduction: The rising demand for pharmaceutical particles with tailored physicochemical
properties has opened new markets for spray drying especially for solubility enhancement …

Three dimensional printing technology is gaining in importance because of its increasing
availability and wide applications. One of the three dimensional printing techniques is Fused …

In this study, aripiprazole (APZ), a weak alkaline drug with pH-dependent solubility, was
selected as model drug to examine the feasibility of preparing nanosuspensions using …

Pharmaceutical cocrystals offer a promising strategy to increase the solubility and
dissolution rate of poorly soluble drugs. However, their manufacturing process requires a …

Echinomycin, a DNA bis-intercalator peptide, belongs to the family of quinoxaline antibiotics.
Echinomycin exhibits potent antitumor and antimicrobial activity. However, it is highly water …

The objective of this study was to formulate aripiprazole (ARI)-loaded pH-modulated solid
dispersions (SD) to enhance solubility, dissolution, and bioavailability via hot-melt extrusion …

Aripiprazole (ARP) is an antipsychotic drug approved for the treatment of schizophrenia. It is
poorly water-soluble and undergoes extensive hepatic metabolism and P-gp efflux, which …

Poor solubility and dissolution property of pharmaceuticals largely limits their bioavailability
and efficacy, and development of a multicomponent crystal is one of the effective …

This research aimed at developing ODFs containing an antipsychotic drug–aripiprazole
(ARP). ARP, as a BCS II class molecule, requires enhancing its water solubility prior to …