Acute lymphoblastic leukemia (ALL), the most common malignancy of childhood, is a
genetically complex entity that remains a major cause of childhood cancer‐related mortality …

Acute lymphoblastic leukemia (ALL) is classified as B‐lineage ALL (B‐ALL) and T‐lineage
ALL (T‐ALL). The incidence of ALL is almost three times higher in white than black children …

Children with Down syndrome (DS) are at a 20-fold increased risk for acute lymphoblastic
leukemia (DS-ALL). Although the etiology of this higher risk of developing leukemia remains …

Summary Background Patients with Down syndrome and acute lymphocytic leukaemia are
at an increased risk of treatment-related mortality and relapse, which is influenced by …

Children with Down syndrome (DS) have a 10-to 20-fold greater predisposition to develop
acute leukemia compared to the general population, with a skew towards myeloid leukemia …

Simple Summary Array analysis is an efficient method for defining in a single experiment all
genome-wide large and fine-scale copy number abnormalities, as well as their …

Pediatric B‐cell acute lymphoblastic leukemia (B‐ALL) is associated with various specific
cytogenetic and molecular markers that have significant influence on treatment and …

Background Hematopoietic stem cell transplantation (HSCT) is one curable option for high‐
risk acute lymphoblastic leukemia (ALL); however, transplant‐related toxicities might be …

Objective The objective of this study is to investigate how lymphoid progenitor mechanisms
contribute to the leukemogenesis in Acute Lymphoblastic Leukemia. Background Acute …

Despite extensive research, the etiology of childhood acute lymphoblastic leukemia (ALL)
remains largely unknown. There is growing evidence that childhood ALL arises from in utero …