Our understanding of the neural crest, a key vertebrate innovation, is built upon studies of
multiple model organisms. Early research on neural crest cells (NCCs) was dominated by …

The peripheral nervous system controls the functions of sensation, movement and motor
coordination of the body. Peripheral nerves can get damaged easily by trauma or …

Neural crest cells are a multipotent embryonic stem cell population that migrate large
distances to contribute a variety of tissues. The cranial neural crest, which contribute to …

The neural crest is a unique, transient stem cell population that is critical for craniofacial and
ocular development. Understanding the genetics underlying the steps of neural crest …

Cranial neural crest cells undergo cellular growth, patterning, and differentiation within the
branchial arches to form cartilage and bone, resulting in a precise pattern of skeletal …

Mesenchymal stem/stromal cells (MSCs) feature promising potential for cellular therapies,
yet significant progress in development of MSC therapeutics and assays is hampered …

Neural crest (NC) cells were described for the first time in 1868 by Wilhelm His. Since then,
this amazing population of migratory stem cells has been intensively studied. It took a …

Neuroblastoma (NB), a childhood cancer arising from the neural crest, poses significant
clinical challenges, particularly in cases featuring amplification of the MYCN oncogene …

Multipass membrane proteins have a myriad of functions, including transduction of cell-cell
signals, ion transport, and photoreception. Insertion of these proteins into the membrane …

Evolutionary innovations are important drivers of speciation and some are the defining
characters of entire phyla. One such major innovation is the carpel, the unifying character …