Type 2 diabetes mellitus (T2DM) continues to be a substantial medical problem due to its
increasing global prevalence and because chronic hyperglycemic states are closely linked …

Abstract Type 2 diabetes (T2D) is a widely prevalent disease with substantial economic and
social impact for which multiple conventional and novel pharmacotherapies are currently …

Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Type 2 bradykinin receptor (B2R) is an essential G protein-coupled receptor (GPCR) that
regulates the cardiovascular system as a vasodepressor. Dysfunction of B2R is also closely …

Bradykinin, a member of the kallikrein–kinin system (KKS), is a potent, short-lived vasoactive
peptide that acts as a vasodilator and an inflammatory mediator in a number of signaling …

Bradykinin, a member of the kallikrein-kinin system (KKS), is associated with an
inflammatory response pathway with diverse vascular permeability functions, including …

Kinins are endogenous peptides that belong to the kallikrein-kinin system, which has been
extensively studied for over a century. Their essential role in multiple physiological and …

Patients with the inherited disorder hereditary angioedema (HAE) suffer from episodes of
soft tissue swelling due to excessive bradykinin production. In most cases, dysregulation of …

The type 2 bradykinin receptor (B2R) is a G protein-coupled receptor (GPCR) in the
cardiovascular system, and the dysfunction of B2R leads to inflammation, hereditary …

Reporter gene imaging (RGI) can accelerate development timelines for gene and viral
therapies by facilitating rapid and noninvasive in vivo studies to determine the …