Acute kidney injury (AKI) arising from diverse etiologies is characterized by mitochondrial
dysfunction. The peroxisome proliferator-activated receptor γ coactivator-1alpha (PGC1α), a …

When in a patient more than one tumour in the same or a different organ is diagnosed,
multiple primary tumours may be present. For epidemiological studies, different definitions of …

Mutations play a fundamental role in the development of cancer, and many create targetable
vulnerabilities. There are both public health and basic science benefits from the …

Background Tri-modality therapy (TMT) is a recognized treatment strategy for selected
patients with muscle-invasive bladder cancer (MIBC). Objective Report long-term outcomes …

Age-related macular degeneration (AMD), a progressive condition that is untreatable in up
to 90% of patients, is a leading cause of blindness in the elderly worldwide. The two forms of …

Breast cancer is the most common neoplasm diagnosed amongst women worldwide and is
the leading cause of female cancer death. However, breast cancer in China is not …

Clinical decisions are more promising and evidence-based, hence, big data analytics to
assist clinical decision-making has been expressed for a variety of clinical fields. Due to the …

Postremission therapy in patients with acute myeloid leukemia (AML) may consist of
continuing chemotherapy or transplantation using either autologous or allogeneic stem …

Context: Telomerase promoter mutations (TERT) were recently described in follicular cell-
derived thyroid carcinomas (FCDTC) and seem to be more prevalent in aggressive cancers …

Purpose Cancer-related fatigue (CRF) is the most prevalent and distressing symptom
among cancer patients and survivors. However, research on its prevalence and related …