Lipid-based nanoparticles in the clinic and clinical trials: from cancer nanomedicine to COVID-19 vaccines

TTH Thi, EJA Suys, JS Lee, DH Nguyen, KD Park… - Vaccines, 2021 - mdpi.com
COVID-19 vaccines have been developed with unprecedented speed which would not have
been possible without decades of fundamental research on delivery nanotechnology. Lipid …

Oral drug delivery platforms for biomedical applications

J Ouyang, Z Zhang, B Deng, J Liu, L Wang, H Liu… - Materials Today, 2023 - Elsevier
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

Solid lipid nanoparticles and nanostructured lipid carriers: A review of the methods of manufacture and routes of administration

J Akbari, M Saeedi, F Ahmadi… - Pharmaceutical …, 2022 - Taylor & Francis
The bioavailability of drugs is dependent on several factors such as solubility and the
administration route. A drug with poor aqueous solubility, therefore, poses challenges with …

Insight on nano drug delivery systems with targeted therapy in treatment of oral cancer

K Vyas, M Rathod, MM Patel - Nanomedicine: Nanotechnology, Biology …, 2023 - Elsevier
Oral cancer is a type of cancer that develops in the mouth and is one of the deadliest
malignancies in the world. Currently surgical, radiation therapy, and chemotherapy are most …

Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours

J Garg, K Pathania, SP Sah, SV Pawar - Future Journal of Pharmaceutical …, 2022 - Springer
Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …

Recent progress in functionalized and targeted polymersomes and chimeric polymeric nanotheranostic platforms for cancer therapy

M Beygi, F Oroojalian, SS Hosseini… - Progress in Materials …, 2023 - Elsevier
The majority of advances in cancer therapy have been achieved based on developments in
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …

[HTML][HTML] Lipid-core nanoparticles: Classification, preparation methods, routes of administration and recent advances in cancer treatment

P Graván, A Aguilera-Garrido, JA Marchal… - Advances in Colloid and …, 2023 - Elsevier
Nanotechnological drug delivery platforms represent a new paradigm for cancer
therapeutics as they improve the pharmacokinetic profile and distribution of …

Folate receptor-mediated delivery of mitoxantrone-loaded solid lipid nanoparticles to breast cancer cells

A Granja, C Nunes, CT Sousa, S Reis - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The standard breast cancer therapy still faces major challenges due to non-specific tumor
distribution and occurrence of dose-limiting adverse side-effects. Nanomedicine constitutes …

Recent progress in nanocarriers for direct nose to brain drug delivery

NA Emad, B Ahmed, A Alhalmi, N Alzobaidi… - Journal of Drug Delivery …, 2021 - Elsevier
Nose to brain drug delivery is considered as a viable option to deliver various therapeutic
agents with low cerebral bioavailability bypass blood-brain barrier (BBB). The drug …

Nanostructured lipid carrier-based codelivery of raloxifene and naringin: formulation, optimization, in vitro, ex vivo, in vivo assessment, and acute toxicity studies

A Alhalmi, S Amin, Z Khan, S Beg, O Al Kamaly… - Pharmaceutics, 2022 - mdpi.com
This work aimed to develop dual drug-loaded nanostructured lipid carriers of raloxifene and
naringin (RLX/NRG NLCs) for breast cancer. RLX/NRG NLCs were prepared using …