The pathophysiology of traumatic brain injury at a glance
M Prins, T Greco, D Alexander… - Disease models & …, 2013 - journals.biologists.com
Traumatic brain injury (TBI) is defined as an impact, penetration or rapid movement of the
brain within the skull that results in altered mental state. TBI occurs more than any other …
brain within the skull that results in altered mental state. TBI occurs more than any other …
Neutrophils in traumatic brain injury (TBI): friend or foe?
YW Liu, S Li, SS Dai - Journal of neuroinflammation, 2018 - Springer
Our knowledge of the pathophysiology about traumatic brain injury (TBI) is still limited.
Neutrophils, as the most abundant leukocytes in circulation and the first-line transmigrated …
Neutrophils, as the most abundant leukocytes in circulation and the first-line transmigrated …
Cerebral ischemia and trauma—different etiologies yet similar mechanisms: neuroprotective opportunities
RR Leker, E Shohami - Brain Research Reviews, 2002 - Elsevier
Cerebral ischemia leads to brain damage caused by pathogenetic mechanisms that are also
activated by neurotrauma. These mechanisms include among others excitotoxicity, over …
activated by neurotrauma. These mechanisms include among others excitotoxicity, over …
Translational neurochemical research in acute human brain injury: the current status and potential future for cerebral microdialysis
L Hillered, PM Vespa, DA Hovda - Journal of neurotrauma, 2005 - liebertpub.com
Microdialysis (MD) was introduced as an intracerebral sampling method for clinical
neurosurgery by Hillered et al. and Meyerson et al. in 1990. Since then MD has been …
neurosurgery by Hillered et al. and Meyerson et al. in 1990. Since then MD has been …
Mitochondrial-based therapeutics for the treatment of spinal cord injury: mitochondrial biogenesis as a potential pharmacological target
NE Scholpa, RG Schnellmann - Journal of Pharmacology and Experimental …, 2017 - ASPET
Spinal cord injury (SCI) is characterized by an initial trauma followed by a progressive
cascade of damage referred to as secondary injury. A hallmark of secondary injury is …
cascade of damage referred to as secondary injury. A hallmark of secondary injury is …
Oxidative stress following traumatic brain injury in rats: quantitation of biomarkers and detection of free radical intermediates
VA Tyurin, YY Tyurina, GG Borisenko… - Journal of …, 2000 - Wiley Online Library
Oxidative stress may contribute to many pathophysiologic changes that occur after traumatic
brain injury. In the current study, contemporary methods of detecting oxidative stress were …
brain injury. In the current study, contemporary methods of detecting oxidative stress were …
Mitochondrial damage and dysfunction in traumatic brain injury
J Lifshitz, PG Sullivan, DA Hovda, T Wieloch… - Mitochondrion, 2004 - Elsevier
The enduring cognitive deficits and histopathology associated with traumatic brain injury
(TBI) may arise from damage to mitochondrial populations, which initiates the metabolic …
(TBI) may arise from damage to mitochondrial populations, which initiates the metabolic …
Temporal characterization of mitochondrial bioenergetics after spinal cord injury
PG Sullivan, S Krishnamurthy, SP Patel… - Journal of …, 2007 - liebertpub.com
Mitochondrial dysfunction following spinal cord injury (SCI) may be critical for the
development of secondary pathophysiology and neuronal cell death. Previous studies have …
development of secondary pathophysiology and neuronal cell death. Previous studies have …
The emerging functions of UCP2 in health, disease, and therapeutics
G Mattiasson, PG Sullivan - Antioxidants & redox signaling, 2006 - liebertpub.com
The uncoupling proteins (UCPs) are attracting an increased interest as potential therapeutic
targets in a number of important diseases. UCP2 is expressed in several tissues, but its …
targets in a number of important diseases. UCP2 is expressed in several tissues, but its …
Synergistic role of oxidative stress and blood-brain barrier permeability as injury mechanisms in the acute pathophysiology of blast-induced neurotrauma
M Kuriakose, D Younger, AR Ravula, E Alay… - Scientific reports, 2019 - nature.com
Blast-induced traumatic brain injury (bTBI) has been recognized as the common mode of
neurotrauma amongst military and civilian personnel due to an increased insurgent activity …
neurotrauma amongst military and civilian personnel due to an increased insurgent activity …