Isobaric labeling-based relative quantification in shotgun proteomics
N Rauniyar, JR Yates III - Journal of proteome research, 2014 - ACS Publications
Mass spectrometry plays a key role in relative quantitative comparisons of proteins in order
to understand their functional role in biological systems upon perturbation. In this review, we …
to understand their functional role in biological systems upon perturbation. In this review, we …
Analysis of the plasma proteome using iTRAQ and TMT‐based Isobaric labeling
R Moulder, SD Bhosale, DR Goodlett… - Mass spectrometry …, 2018 - Wiley Online Library
Over the past decade, chemical labeling with isobaric tandem mass tags, such as isobaric
tags for relative and absolute quantification reagents (iTRAQ) and tandem mass tag (TMT) …
tags for relative and absolute quantification reagents (iTRAQ) and tandem mass tag (TMT) …
[HTML][HTML] Mass spectrometry-assisted gel-based proteomics in cancer biomarker discovery: approaches and application
R Huang, Z Chen, L He, N He, Z Xi, Z Li, Y Deng… - Theranostics, 2017 - ncbi.nlm.nih.gov
There is a critical need for the discovery of novel biomarkers for early detection and targeted
therapy of cancer, a major cause of deaths worldwide. In this respect, proteomic …
therapy of cancer, a major cause of deaths worldwide. In this respect, proteomic …
[HTML][HTML] Gut mucosal proteins and bacteriome are shaped by the saturation index of dietary lipids
The dynamics of the tripartite relationship between the host, gut bacteria and diet in the gut
is relatively unknown. An imbalance between harmful and protective gut bacteria, termed …
is relatively unknown. An imbalance between harmful and protective gut bacteria, termed …
Proteomic advances in salivary diagnostics
Saliva is identified as functional equivalent to serum, reflecting the physiological state of the
body, as well as hormonal, emotional, nutritional and metabolic alterations. The application …
body, as well as hormonal, emotional, nutritional and metabolic alterations. The application …
A comparative proteomic study of human skin suction blister fluid from healthy individuals using immunodepletion and iTRAQ labeling
AC Müller, FP Breitwieser, H Fischer… - Journal of proteome …, 2012 - ACS Publications
Aberrations in skin morphology and functionality can cause acute and chronic skin-related
diseases that are the focus of dermatological research. Mechanically induced skin suction …
diseases that are the focus of dermatological research. Mechanically induced skin suction …
[HTML][HTML] Proteomics for prediction of disease progression and response to therapy in diabetic kidney disease
The past decade has resulted in multiple new findings of potential proteomic biomarkers of
diabetic kidney disease (DKD). Many of these biomarkers reflect an important role in the …
diabetic kidney disease (DKD). Many of these biomarkers reflect an important role in the …
Serum proteomes distinguish children developing type 1 diabetes in a cohort with HLA-conferred susceptibility
We determined longitudinal serum proteomics profiles from children with HLA-conferred
diabetes susceptibility to identify changes that could be detected before seroconversion and …
diabetes susceptibility to identify changes that could be detected before seroconversion and …
Mass spectrometry-based proteomic quest for diabetes biomarkers
S Shao, T Guo, R Aebersold - … et Biophysica Acta (BBA)-Proteins and …, 2015 - Elsevier
Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia,
which affects hundreds of millions of individuals worldwide. Early diagnosis and …
which affects hundreds of millions of individuals worldwide. Early diagnosis and …
Beneficial effects of phlorizin on diabetic nephropathy in diabetic db/db mice
F Pei, B Li, Z Zhang, F Yu, X Li, Q Cai, H Gao… - Journal of Diabetes and …, 2014 - Elsevier
Aims This study observes the effects of phlorizin on diabetic nephrology in db/db diabetic
mice and explores possible underlying mechanisms. Methods Sixteen diabetic db/db mice …
mice and explores possible underlying mechanisms. Methods Sixteen diabetic db/db mice …