Deconstructing virus condensation

N Lopez, G Camporeale, M Salgueiro… - PLoS …, 2021 - journals.plos.org
Viruses have evolved precise mechanisms for using the cellular physiological pathways for
their perpetuation. These virus-driven biochemical events must be separated in space and …

Yellow dwarf viruses of cereals: taxonomy and molecular mechanisms

WA Miller, Z Lozier - Annual Review of Phytopathology, 2022 - annualreviews.org
Yellow dwarf viruses are the most economically important and widespread viruses of cereal
crops. Although they share common biological properties such as phloem limitation and …

Co‐opted cytosolic proteins form condensate substructures within membranous replication organelles of a positive‐strand RNA virus

W Lin, PD Nagy - New Phytologist, 2024 - Wiley Online Library
Positive‐strand RNA viruses co‐opt organellar membranes for biogenesis of viral replication
organelles (VROs). Tombusviruses also co‐opt pro‐viral cytosolic proteins to VROs. It is …

Crowning touches in positive-strand RNA virus genome replication complex structure and function

M Nishikiori, JA den Boon… - Annual Review of …, 2022 - annualreviews.org
Positive-strand RNA viruses, the largest genetic class of eukaryotic viruses, include
coronaviruses and many other established and emerging pathogens. A major target for …

Out of the ESCPE room: emerging roles of endosomal SNX‐BARs in receptor transport and host–pathogen interaction

B Simonetti, JL Daly, PJ Cullen - Traffic, 2023 - Wiley Online Library
Several functions of the human cell, such as sensing nutrients, cell movement and
interaction with the surrounding environment, depend on a myriad of transmembrane …

Turnip mosaic virus co-opts the vacuolar sorting receptor VSR4 to promote viral genome replication in plants by targeting viral replication vesicles to the endosome

G Wu, Z Jia, K Ding, H Zheng, Y Lu, L Lin… - PLoS …, 2022 - journals.plos.org
Accumulated experimental evidence has shown that viruses recruit the host intracellular
machinery to establish infection. It has recently been shown that the potyvirus Turnip mosaic …

Co-opted membranes, lipids, and host proteins: what have we learned from tombusviruses?

PD Nagy - Current Opinion in Virology, 2022 - Elsevier
Highlights•Tomato bushy stunt virus builds unique membranous replication organelles that
provide optimal lipid microenvironment.•Tombusviruses co-opt pre-existing subcellular …

Exogenous and endogenous dsRNAs perceived by plant Dicer-like 4 protein in the RNAi-depleted cellular context

P Leonetti, A Consiglio, D Arendt, RP Golbik… - Cellular & Molecular …, 2023 - Springer
Abstract Background In plants, RNase III Dicer-like proteins (DCLs) act as sensors of
dsRNAs and process them into short 21-to 24-nucleotide (nt)(s) RNAs. Plant DCL4 is …

RETICULON-LIKE PROTEIN B2 is a proviral factor co-opted for the biogenesis of viral replication organelles in plants

Q Zhang, Z Wen, X Zhang, J She, X Wang, Z Gao… - The Plant …, 2023 - academic.oup.com
Endomembrane remodeling to form a viral replication complex (VRC) is crucial for a virus to
establish infection in a host. Although the composition and function of VRCs have been …

Manipulation of the cellular membrane-cytoskeleton network for RNA virus replication and movement in plants

R He, Y Li, MA Bernards, A Wang - Viruses, 2023 - mdpi.com
Viruses infect all cellular life forms and cause various diseases and significant economic
losses worldwide. The majority of viruses are positive-sense RNA viruses. A common …